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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

(d)CMP kinaza
(d)CMP kinaza
Identifikatori
EC broj	2.7.4.25
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

(d)CMP kinaza (EC 2.7.4.25, prokariotska citidilatna kinaza, dezoksicitidilatna kinaza, dCMP kinaza, dezoksicitidinna monofosfokinaza) je enzim sa sistematskim imenom ATP:(d)CMP fosfotransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + (d)CMP

\rightleftharpoons

ADP + (d)CDP

Prokariotska citidin monofosfatna kinaza specifično fosforiliše CMP (ili dCMP), koristeći ATP kao preferentni fosforilni donor.

Reference

^ Bertrand T, Briozzo P, Assairi L, Ofiteru A, Bucurenci N, Munier-Lehmann H, Golinelli-Pimpaneau B, Barzu O, Gilles AM (2002). „Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme”. J. Mol. Biol. 315: 1099—1110. PMID 11827479.
^ Thum C, Schneider CZ, Palma MS, Santos DS, Basso LA (2009). „The Rv1712 Locus from Mycobacterium tuberculosis H37Rv codes for a functional CMP kinase that preferentially phosphorylates dCMP”. J. Bacteriol. 191: 2884—2887. PMID 19181797.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

(d)CMP+kinase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Bertrand T, Briozzo P, Assairi L, Ofiteru A, Bucurenci N, Munier-Lehmann H, Golinelli-Pimpaneau B, Barzu O, Gilles AM (2002). „Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme”. J. Mol. Biol. 315: 1099—1110. PMID 11827479.

[2] Thum C, Schneider CZ, Palma MS, Santos DS, Basso LA (2009). „The Rv1712 Locus from Mycobacterium tuberculosis H37Rv codes for a functional CMP kinase that preferentially phosphorylates dCMP”. J. Bacteriol. 191: 2884—2887. PMID 19181797.

[1]

[2]