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(R)-3-amino-2-metilpropionat-piruvat transaminaza
(R)-3-amino-2-metilpropionat-piruvat transaminaza
Identifikatori
EC broj	2.6.1.40
CAS broj	37279-00-8
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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(R)-3-amino-2-metilpropionat-piruvat transaminaza (EC 2.6.1.40, D-3-aminoizobutirat-piruvatna transaminaza, beta-aminoizobutirat-piruvatna aminotransferaza, D-3-aminoizobutirat-piruvatna aminotransferaza, D-3-aminoizobutirat-piruvatna transaminaza, (R)-3-amino-2-metilpropionatna transaminaza, D-beta-aminoizobutirat:piruvatna aminotransferaza) je enzim sa sistematskim imenom (R)-3-amino-2-metilpropanoat:piruvat aminotransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

(R)-3-amino-2-metilpropanoat + piruvat

\rightleftharpoons

2-metil-3-oksopropanoat + L-alanin

Ovaj enzim, zajedno sa EC 2.6.1.22, (S)-3-amino-2-metilpropionat transaminazom, posreduje interkonverziju enantiomera 3-amino-2-metilpropanoata.

Reference

^ Kakimoto, Y., Taniguchi, K. and Sano, I. (1969). „D-β-Aminoisobutyrate:pyruvate aminotransferase in mammalian liver and excretion of β-aminoisobutyrate by man”. J. Biol. Chem. 244: 335—340. PMID 5773299.
^ Tamaki, N., Sakata, S.F. and Matsuda, K. (2000). „Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver”. Methods Enzymol. 324: 376—389. PMID 10989446.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

(R)-3-amino-2-methylpropionate---pyruvate+transaminase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Kakimoto, Y., Taniguchi, K. and Sano, I. (1969). „D-β-Aminoisobutyrate:pyruvate aminotransferase in mammalian liver and excretion of β-aminoisobutyrate by man”. J. Biol. Chem. 244: 335—340. PMID 5773299.

[2] Tamaki, N., Sakata, S.F. and Matsuda, K. (2000). „Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver”. Methods Enzymol. 324: 376—389. PMID 10989446.

[1]

[2]