Indianapolis 500 1978 je bila dvainšestdeseta dirka Indianapolis 500 na dirkališču Indianapolis. Potekala je 28. maja 1978.

Mesto	Št. mesto	Št	Dirkač	Kval	Rang	Krogi	Vodstvo	Status
1	5	2	Al Unser	196.474	7	200	121	V cilju
2	1	1	Tom Sneva	202.156	1	200	3	V cilju
3	6	20	Gordon Johncock	195.833	8	199	0	V cilju
4	13	40	Steve Krisiloff	191.255	19	198	5	V cilju
5	7	6	Wally Dallenbach, Sr.	195.233	9	195	0	V cilju
6	19	48	Bobby Unser	194.658	10	195	0	V cilju
7	20	14	A.J. Foyt	200.122	2	191	0	V cilju
8	23	84	George Snider	192.626	16	191	0	V cilju
9	15	51	Janet Guthrie	190.325	22	190	0	V cilju
10	8	16	Johnny Parsons	194.280	12	186	0	V cilju
11	30	35	Larry Rice	187.392	31	186	0	Motor
12	33	7	Mario Andretti	194.647	11	185	0	V cilju
13	4	4	Johnny Rutherford	197.098	5	180	0	V cilju
14	28	88	Jerry Karl	187.549	29	176	0	V cilju
15	24	69	Joe Saldana	190.809	21	173	0	V cilju
16	31	98	Gary Bettenhausen	187.324	32	147	0	Motor
17	25	78	Mike Mosley	188.719	26	146	0	Motor
18	2	25	Danny Ongais	200.122	3	145	71	Motor
19	10	17	Dick Simon	192.967	15	138	0	Obesa
20	26	26	Jim McElreath	188.058	27	132	0	Motor
21	18	43	Tom Bigelow	189.115	25	107	0	Pog. gred
22	9	80	Larry Dickson	193.434	13	104	0	Pritisk olja
23	3	71	Rick Mears	200.078	4	103	0	Motor
24	21	8	Pancho Carter	196.829	6	92	0	Header
25	11	11	Roger McCluskey	192.256	17	82	0	Sklopka
26	17	39	John Mahler	189.723	24	58	0	Menjalnik
27	14	22	Tom Bagley	190.941	20	25	0	Puščanje olja
28	22	77	Salt Walther	193.226	14	24	0	Sklopka
29	16	19	Spike Gehlhausen	190.325	23	23	0	Trčenje
30	29	47	Phil Threshie	187.520	30	22	0	Pritisk olja
31	32	30	Jerry Sneva	187.266	33	18	0	Prenos
32	12	24	Sheldon Kinser	192.051	18	15	0	Pritisk olja
33	27	29	Cliff Hucul	187.805	28	4	0	Olje