L-isomer of Tryptophan Tryptophan (Trp or W ) is encoded by the codon UGG . It is an α-amino acid used in the biosynthesis of proteins .
Tryptophan has an α-amino group (which is in the –NH3 + form under biological conditions), and an α-carboxylic acid group (which is in the deprotonated –COO− form under biological conditions). It also has a side chain indole , which makes it a non-polar aromatic amino acid. Tryptophan is essential to humans: the body cannot synthesize it, so it must be got from the diet.
Tryptophan is also a precursor to the neurotransmitters serotonin and melatonin .[ 1]
People get tryptophan by eating protein-rich foods like meat, eggs, and dairy products.
References
↑ Slominski, Andrzej; Semak, Igor; Pisarchik, Alexander; Sweatman, Trevor; Szczesniewski, Andre; Wortsman, Jacobo (2002). "Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells". FEBS Letters . 511 (1–3): 102–6. doi :10.1016/s0014-5793(01)03319-1 . PMID 11821057 . S2CID 7820568 .
General topics By properties
AhR
Agonists: Dietary carotenoids Halogenated aromatic hydrocarbons (e.g., polychlorinated dibenzodioxins (e.g., TCDD ), dibenzofurans , biphenyls )Tetrapyroles (e.g., bilirubin )Tryptophan derivatives (e.g., indigo dye , indirubin )Arachidonic acid metabolites (e.g., lipoxin A4 , prostaglandin G2 )Flutamide ΙΤΕ Modified low-density lipoproteins Polycyclic aromatic hydrocarbons (e.g., 3-methylcholanthrene , benzo[a]pyrene , benzanthracenes , benzoflavones (e.g., β-naphthoflavone ))Tapinarof (benvitimod)
