Abandoned by his parents and raised by an aunt and uncle, teenager Peter Parker (Andrew Garfield) is trying to figure out why his parents left. When Peter finds a mysterious briefcase that was his father's, he tries to figure out what it means. His search takes him to Oscorp and the lab of Dr. Curt Connors who created a genetically engineeredspider which bites Peter Parker and gives him superpowers. After his uncle Ben Parker is murdered, Peter becomes a Superhero called Spider-Man. Peter falls in love with Gwen Stacy whose policeman father hates Spider-Man. Dr. Connors transforms himself into a Supervillain called The Lizard and Spider-Man stops the Lizard from turning everyone in New York City into a Lizard.
