Pfizer(/ˈfaɪzər/)[3] is an American pharmaceutical corporation. One of the world's largest pharmaceutical companies, it is ranked 64 on the 2020 Fortune 500 list of the largest United States corporations by total revenue.[4][5] It was founded in 1849 in New York City. It is ranked the largest drug company in the world. The company is responsible for the first COVID-19 vaccination. Pfizer is known for its drugs Advil and ChapStick. The company bought Wyeth, which also used to be a drug company. The deal was completed in 2009.