Brian Hull as Count "Drac" Dracula, the founder of Hotel Transylvania and Mavis' father, Johnny's father-in-law, Vlad's son, and Dennis' maternal grandfather. He was originally voiced by Adam Sandler in the first three films.[1][2]
Andy Samberg as Johnathan "Johnny" Loughran, Mavis' husband, Dracula's son-in-law, and Dennis' father.[2]
Selena Gomez as Mavis Dracula, Johnny's wife, Dracula's daughter and Dennis' mother.[2]
Asher Blinkoff as Dennis, the son of Johnny and Mavis, and Dracula's grandson.[2]
Brad Abrell as Frankenstein, Eunice's husband. He was originally voiced by Kevin James in the first three films.[3]
Zoe Berri as Winnie, a werewolf who is the daughter of Wayne and Wanda and a friend of Dennis. She was originally voiced by Sadie Sandler in the first three films.
Asher Bishop as Wesley, a werewolf who is the son of Wayne and Wanda.
Richard Tyler "Ninja" Blevins as Party Monster.
Genndy Tartakovsky as Blobby, a green blob monster.
Victoria Gomez as Wilma
Jennifer Kluska as Wendy
Derek Drymon as a zombie that was briefly turned into a human