The club was founded in 1944.[2]
León won the Primera División title seven times: in 1948, 1949, 1952, 1956, 1992, Apertura 2013 and most recently Clausura 2014. They became the first Mexican "Campeonísimo" (winner of the League and the Copa México in the same year) in 1949. In 1993 León was the CONCACAF Champions' Cup runner-up, losing the to the Costa Rican team Deportivo Saprissa.