"Chain Reaction" is a 1990 song by Australian singer John Farnham and is the lead single from his 14th studio album Chain Reaction. It went to number 6 in Australia, number 21 in New Zealand and number 79 in the Netherlands.

Australian CD and 7-inch single

1. "Chain Reaction" – 3:12
2. "In Your Hands" – 4:19

12-inch single

1. "Chain Reaction" (Tex mix) – 6:07
2. "In Days to Come" – 4:01
3. "Chain Reaction" (radio mix) – 3:12

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