A human chain can be made by people standing next to one another and who hold hands or link arms. It is a chain that has people for its links.
Chain store, retail stores which share a brand and central management, usually with standardized business methods and practices. They may all have the same owners or may be franchised.
This disambiguation page lists articles associated with the title Chain. If an internal link led you here, you may wish to change the link to point directly to the intended article.