Carlisle, Massachusetts
Town
Downtown Carlisle in 2009
Seal Logo
Location in Middlesex County in Massachusetts
Coordinates: 42°31′45″N 71°21′00″W / 42.52917°N 71.35000°W / 42.52917; -71.35000
Country	United States
State	Massachusetts
County	Middlesex
Settled	1651
Incorporated	1805
Area
• Total	15.6 sq mi (40.2 km2)
• Land	15.4 sq mi (39.8 km2)
• Water	0.2 sq mi (0.4 km2)
Elevation	205 ft (62 m)
Population  (2020)
• Total	5,237
• Density	340.1/sq mi (131.6/km2)
Time zone	UTC-5 (Eastern)
• Summer (DST)	UTC-4 (Eastern)
ZIP code	01741
Area code	351 / 978
FIPS code	25-11525
GNIS feature ID	0619397
Website	www.carlislema.gov

Carlisle is a small town in Middlesex County, Massachusetts, United States. As of 2025, Its population was 5,192

Carlisle was first settled in 1651. It became a part of Concord in 1780. It became a town in 1805. When people first starting to live at Carlisle, it belonged to Acton, Billerica, Chelmford and Concord.

Carlisle is about eight miles south-southwest of Lowell, and 23 miles northwest of Boston.

• History of Middlesex County, Massachusetts, compiled by Samuel Adams Drake, published 1879. Volume 1, page 359 Carlisle by B.F.Heald.

• carlislema.gov, the official Town of Carlisle website
• carlisle.org, a volunteer-run Carlisle community website
• The Carlisle Mosquito, the town newspaper
• Carlisle Conservation Foundation
• Carlisle Public School