2010 US Open
Champion		Liezel Huber Bob Bryan
Runner-up		Květa Peschke Aisam-ul-Haq Qureshi
Final score		6–4, 6–4
Events
Singles		men		women				boys		girls
Doubles		men		women		mixed		boys		girls
Other events
Legends		men		women		mixed
WC Singles		men		women		quad
WC Doubles		men		women		quad

Carly Gullickson and Travis Parrott were the defending champions, but lost in the first round to Gisela Dulko and Pablo Cuevas 2–6, 4–6.

Liezel Huber and Bob Bryan won in the final 6–4, 6–4, against Květa Peschke and Aisam-ul-Haq Qureshi.

	Semifinals							Final
	1	Liezel Huber   Bob Bryan	6	7
	4	Bethanie Mattek-Sands   Daniel Nestor	3	5
								1	Liezel Huber   Bob Bryan	6	6
									Květa Peschke   Aisam-ul-Haq Qureshi	4	4
		Květa Peschke   Aisam-ul-Haq Qureshi	7	7
		Anna-Lena Grönefeld   Mark Knowles	65	64

First Round							Second Round							Quarterfinals							Semifinals
1	L Huber   B Bryan	6	6
ALT	S-w Hsieh   B Soares	4	3				1	L Huber   B Bryan	5	6	[10]
WC	M Oudin   R Harrison	6	7				WC	M Oudin   R Harrison	7	1	[3]
	A Hlaváčková   M Mertiňák	1	5											1	L Huber   B Bryan	6	7
	T Bacsinszky   O Marach	1	3											7	L Raymond   W Moodie	4	63
	O Govortsova   M Matkowski	6	6					O Govortsova   M Matkowski	4	65
	A Medina Garrigues   M López	1	64				7	L Raymond   W Moodie	6	7
7	L Raymond   W Moodie	6	7																		1	L Huber   B Bryan	6	7
4	B Mattek-Sands   D Nestor	6	2	[10]																	4	B Mattek-Sands   D Nestor	3	5
WC	B Capra   J Sock	2	6	[7]			4	B Mattek-Sands   D Nestor	62	6	[10]
	Z Yan   R Bopanna	2	4					A Rezaï   R Ram	7	2	[5]
	A Rezaï   R Ram	6	6											4	B Mattek-Sands   D Nestor	6	6
	Y-j Chan   P Hanley	6	6												Y-j Chan   P Hanley	4	3
ALT	A Dulgheru   D Marrero	4	2					Y-j Chan   P Hanley	6	5	[10]
WC	A Spears   S Lipsky	7	7				WC	A Spears   S Lipsky	2	7	[5]
5	R Stubbs   D Norman	64	63

First Round							Second Round							Quarterfinals							Semifinals
8	V King   H Tecău	5	6	[5]
	K Peschke   A-u-H Qureshi	7	4	[10]				K Peschke   A-u-H Qureshi	5	6	[10]
WC	J Craybas   M Russell	63	7	[1]				Y Shvedova   J Knowle	7	3	[4]
	Y Shvedova   J Knowle	7	5	[10]											K Peschke   A-u-H Qureshi	3	6	[10]
WC	C Gullickson   T Parrott	2	4												G Dulko   P Cuevas	6	2	[4]
	G Dulko   P Cuevas	6	6					G Dulko   P Cuevas	7	7
	A Petkovic   M Fyrstenberg	63	62				3	K Srebotnik   N Zimonjić	5	5
3	K Srebotnik   N Zimonjić	7	7																			K Peschke   A-u-H Qureshi	7	7
6	E Vesnina   A Ram	6	66	[11]																		A-L Grönefeld   M Knowles	65	64
WC	R Kops-Jones   E Butorac	4	7	[9]			6	E Vesnina   A Ram	6	3	[7]
	A-L Grönefeld   M Knowles	6	6					A-L Grönefeld   M Knowles	4	6	[10]
WC	N Gibbs   S Querrey	3	2												A-L Grönefeld   M Knowles	6	6
	D Hantuchová   M Bhupathi	4	2											2	C Black   L Paes	3	4
	K Kanepi   R Lindstedt	6	6					K Kanepi   R Lindstedt	4	1
	L Hradecká   F Čermák	4	5				2	C Black   L Paes	6	6
2	C Black   L Paes	6	7

• Official site of US Open