1533 (MDXXXIII) was a common year starting on Wednesday of the Julian calendar, the 1533rd year of the Common Era (CE) and Anno Domini (AD) designations, the 533rd year of the 2nd millennium, the 33rd year of the 16th century, and the 4th year of the 1530s decade. As of the start of 1533, the Gregorian calendar was 10 days ahead of the Julian calendar, which was the dominant calendar of the time.

• Ottoman-Habsburg War in Hungary
• January 25– Henry VIII marries Anne Boleyn

• September 7 – Elizabeth I of England

• June 25 – Mary Tudor