Zingipain

Zingipain
Identifikatori
EC broj 3.4.22.67
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Zingipain (EC 3.4.22.67, đimburna proteaza, GP-I, GP-II, đimburna proteaza II (Zingiber officinale), zingibain) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Preferentno razlaganje peptida sa prolinskim ostatko u P2 poziciji

Ovaj enzim je prisutanu đimburu (Zingiber officinale) i član je papainske familije.

Reference

  1. ↑ Choi, K.H. and Laursen, R.A. (2000). „Amino-acid sequence and glycan structures of cysteine proteases with proline specificity from ginger rhizome Zingiber officinale”. Eur. J. Biochem. 267: 1516-1526. PMID 10691991. 
  2. ↑ Ohtsuki, K., Taguchi, K., Sato, K. and Kawabata, M. (1995). „Purification of ginger proteases by DEAE-Sepharose and isoelectric focusing”. Biochim. Biophys. Acta 1243: 181-184. PMID 7873561. 
  3. ↑ Choi, K.H., Laursen, R.A. and Allen, K.N. (1999). „The 2.1 Å structure of a cysteine protease with proline specificity from ginger rhizome, Zingiber officinale”. Biochemistry 38: 11624-11633. PMID 10512617. 

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