UDP-4-amino-4-dezoksi-L-arabinoza aminotransferaza

UDP-4-amino-4-dezoksi-L-arabinoza aminotransferaza
Identifikatori
EC broj 2.6.1.87
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

UDP-4-amino-4-dezoksi-L-arabinoza aminotransferaza (EC 2.6.1.87, UDP-(beta-L-treo-pentapiranozil-4-uloza difosfat) aminotransferaza, UDP-4-amino-4-dezoksi-L-arabinoza---oksoglutarat aminotransferaza, UDP-Ara4O aminotransferaza, UDP-L-Ara4N transaminaza) je enzim sa sistematskim imenom UDP-4-amino-4-dezoksi-beta-L-arabinoza:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

UDP-4-amino-4-dezoksi-beta-L-arabinopiranoza + 2-oksoglutarat UDP-beta-L-treo-pentapiranoz-4-uloza + L-glutamat

Ovaj enzim je piridoksal 5'-fosfatni enzim.

Reference

  1. Breazeale, S.D., Ribeiro, A.A. and Raetz, C.R. (2003). „Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose”. J. Biol. Chem. 278: 24731-24739. PMID 12704196. 
  2. Noland, B.W., Newman, J.M., Hendle, J., Badger, J., Christopher, J.A., Tresser, J., Buchanan, M.D., Wright, T.A., Rutter, M.E., Sanderson, W.E., Muller-Dieckmann, H.J., Gajiwala, K.S. and Buchanan, S.G. (2002). „Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme”. Structure 10: 1569-1580. PMID 12429098. 

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