Tubulinska GTPaza

Tubulinska GTPaza
Identifikatori
EC broj 3.6.5.6
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Tubulinska GTPaza (EC 3.6.5.6) je enzim sa sistematskim imenom GTP fosfohidrolaza (oslovađanje mikrotubule).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

GTP + H2O GDP + fosfat

Ovaj enzim učestvuje u savijanju tubulina.

Reference

  1. ↑ Yu, X.C. and Margolin, W. (1997). „Ca2+-mediated GTP-dependent dynamic assembly of bacetrial cell division protein FtsZ into asters and polymer networks in vitro”. EMBO J. 16: 5455-5463. PMID 9312004. 
  2. ↑ Tian, G., Bhamidipati, A., Cowan, N.J. and Lewis, S.A. (1999). „Tubulin folding cofactors as GTPase-activating proteins. GTP hydrolysis and the assembly of the α/β-tubulin heterodimer”. J. Biol. Chem. 274: 24054-24058. PMID 10446175. 
  3. ↑ Roychowdhury, S., Panda, D., Wilson, L. and Rasenick, M.M. (1999). „G protein α subunits activate tubulin GTPase and modulate microtubule polymerization dynamics”. J. Biol. Chem. 274: 13485-13490. PMID 10224115. 

Literatura

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