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Transportna ATPaza mitohondrijalnog proteina
Identifikatori
EC broj	3.6.3.51
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Transportna ATPaza mitohondrijalnog proteina (EC 3.6.3.51) je enzim sa sistematskim imenom ATP fosfohidrolaza (import mitohondrijskog proteina).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + H₂O

\rightleftharpoons

ADP + fosfat

Ova nefosforilisana ATPaza učestvuje u transportu proteina.

Reference

↑ Bomer, U., Meijer, M., Maarse, A.C., Honlinger, A., Dekker, P.J., Pfanner, N. and Rassow, J. (1997). „Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane”. EMBO J. 16: 2205-2216. PMID 9171336.
↑ Berthold, J., Bauer, M.F., Schneider, H.C., Klaus, C., Dietmeier, K., Neupert, W. and Brunner, M. (1995). „The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP-driving system”. Cell 81: 1085-1093. PMID 7600576.
↑ Voos, W., Martin, H., Krimmer, T. and Pfanner, N. (1999). „Mechanisms of protein translocation into mitochondria”. Biochim. Biophys. Acta 1422: 235-254. PMID 10548718.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Mitochondrial+protein-transporting+ATPase

[1] Bomer, U., Meijer, M., Maarse, A.C., Honlinger, A., Dekker, P.J., Pfanner, N. and Rassow, J. (1997). „Multiple interactions of components mediating preprotein translocation across the inner mitochondrial membrane”. EMBO J. 16: 2205-2216. PMID 9171336.

[2] Berthold, J., Bauer, M.F., Schneider, H.C., Klaus, C., Dietmeier, K., Neupert, W. and Brunner, M. (1995). „The MIM complex mediates preprotein translocation across the mitochondrial inner membrane and couples it to the mt-Hsp70/ATP-driving system”. Cell 81: 1085-1093. PMID 7600576.

[3] Voos, W., Martin, H., Krimmer, T. and Pfanner, N. (1999). „Mechanisms of protein translocation into mitochondria”. Biochim. Biophys. Acta 1422: 235-254. PMID 10548718.

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