Scitalonska dehidrataza

Scitalonska dehidrataza
Identifikatori
EC broj 4.2.1.94
CAS broj 118901-79-4
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Scitalonska dehidrataza (EC 4.2.1.94, scitalonska 7,8-hidrolijaza) je enzim sa sistematskim imenom scitalon 7,8-hidrolijaza (formira 1,3,8-trihidroksinaftalen).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

scitalon 1,3,8-trihidroksinaftalen + H2O

Ovaj enzim zajedno sa enzimom EC 1.1.1.252, tetrahidroksinaftalenskom reduktazom, učestvuje u biosintezi melanina u patogenim gljivama.

Reference

  1. Butler, M.J., Lazarovits, G., Higgins, V.J. and Lachance, M.-A. (1988). „Partial-purification and characterization of a dehydratase associated with the pentaketide melanogenesis pathway of Phaeococcomyces sp and other fungi”. Exp. Mycol. 12: 367-376. 
  2. Tajima, S., Kubo, Y., Furusawa, I. and Shishiyama, J. (1989). „Purification of a melanin biosynthetic enzyme converting scytalone to 1,3,8-trihydroxynaphthalene from Cochliobolus miyabeanus”. Exp. Mycol. 13: 69-69. 
  3. Wheeler, M.H. and Greenblatt, G.A. (1988). „The inhibition of melanin biosynthetic reactions in Pyricularia oryzae' by compounds that prevent rice blast disease”. Exp. Mycol. 12: 151-160. 

Literatura

Vanjske veze