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Oploforus-luciferin 2-monooksigenaza
Identifikatori
EC broj	1.13.12.13
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Oploforus-luciferin 2-monooksigenaza (EC 1.13.12.13, Oplophorus luciferaza) je enzim sa sistematskim imenom Oplophorus-luciferin:kiseonik 2-oksidoreduktaza (dekarboksilacija).^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Oplophorus luciferin + O₂

\rightleftharpoons

oksidovani Oplophorus luciferin + CO₂ + hnu

Luciferaza iz dubinske lignje Oplophorus gracilorostris je kompleks koji se sastoji od više proteina. Enzim ima široku specifičnost. Koelenterazin i bisdezoksikoelenterazin su dobri supstrati.

Reference

↑ Shimomura, O., Masugi, T., Johnson, F.H. and Haneda, Y. (1978). „Properties and reaction mechanism of the bioluminescence system of the deep-sea shrimp Oplophorus gracilorostris”. Biochemistry 17: 994-998. PMID 629957.
↑ Inouye, S., Watanabe, K., Nakamura, H., Shimomura, O. (2000). „Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase”. FEBS Lett. 481: 19-25. PMID 10984608.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Oplophorus-luciferin+2-monooxygenase

[1] Shimomura, O., Masugi, T., Johnson, F.H. and Haneda, Y. (1978). „Properties and reaction mechanism of the bioluminescence system of the deep-sea shrimp Oplophorus gracilorostris”. Biochemistry 17: 994-998. PMID 629957.

[2] Inouye, S., Watanabe, K., Nakamura, H., Shimomura, O. (2000). „Secretional luciferase of the luminous shrimp Oplophorus gracilirostris: cDNA cloning of a novel imidazopyrazinone luciferase”. FEBS Lett. 481: 19-25. PMID 10984608.

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