O-fukozilpeptid 3-b-N-acetilglukozaminiltransferaza

O-fukozilpeptid 3-b-N-acetilglukozaminiltransferaza
Identifikatori
EC broj 2.4.1.222
CAS broj 299203-70-6
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

O-fukozilpeptid 3-b-N-acetilglukozaminiltransferaza (EC 2.4.1.222, O-fukozilpeptidna beta-1,3-N-acetilglukozaminiltransferaza) je enzim sa sistematskim imenom UDP-D-GlcNAc:O-L-fukozilpeptid 3-beta-N-acetil-D-glukozaminiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

prenosi beta-D-GlcNAc ostatak sa UDP-D-GlcNAc na fukozni ostatak fukozilisanog proteinskog akceptora

O-fukozilpeptid 3-beta-N-acetilglukozaminiltransferazas su produkti ivičnig (engl. fringe) gena.

Reference

  1. Moloney, D.J., Panin, V.M., Johnston, S.H., Chen, J., Shao, L., Wilson, R., Wang, Y., Stanley, P., Irvine, K.D., Haltiwanger, R.S. and Vogt, T.F. (2000). „Fringe is a glycosyltransferase that modifies Notch”. Nature 406: 369-375. PMID 10935626. 

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