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Mitohondrijalna intermedijarna peptidaza
Identifikatori
EC broj	3.4.24.59
CAS broj	136447-30-8
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Mitohondrijalna intermedijarna peptidaza (EC 3.4.24.59, proteinaza transformacije mitohondrijskog intermedijernog prekursorA, MIP) je enzim.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Razlaganje N-terminalnog oktapeptida kao sekondni stupanj transformacije pojedinih proteina unesenih u mitohondrije

Ovaj enzim je homolog timetne oligopeptidaze.

Reference

↑ Isaya, G., Kalousek, F. and Rosenberg, L.E. (1992). „Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase”. J. Biol. Chem. 267: 7904-7910. PMID 1560019.
↑ Isaya, G., Kalousek, F. and Rosenberg, L.E. (1992). „Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue”. Proc. Natl. Acad. Sci. USA 89: 8317-8321. PMID 1518864.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Mitochondrial+intermediate+peptidase

[1] Isaya, G., Kalousek, F. and Rosenberg, L.E. (1992). „Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase”. J. Biol. Chem. 267: 7904-7910. PMID 1560019.

[2] Isaya, G., Kalousek, F. and Rosenberg, L.E. (1992). „Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue”. Proc. Natl. Acad. Sci. USA 89: 8317-8321. PMID 1518864.

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