Metanol—5-hidroksibenzimidazolilkobamid Co-metiltransferaza

Metanol—5-hidroksibenzimidazolilkobamid Co-metiltransferaza
Identifikatori
EC broj 2.1.1.90
CAS broj 86611-98-5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Metanol—5-hidroksibenzimidazolilkobamid Co-metiltransferaza (EC 2.1.1.90, metanol kobalaminska metiltransferaza, metanol:5-hidroksibenzimidazolilkobamidna metiltransferaza, MT 1 (nespecifična), metanol 5-hidroksibenzimidazolilkobamidna Co-metiltransferaza, mtaB (gen)) je enzim sa sistematskim imenom metanol:5-hidroksibenzimidazolilkobamid Co-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

metanol+ [Co(I) metanol-specifični korinoidni protein] [metil-Co(III) metanol-specifični korinoidni protein] + H2O

Enzim, koji katalizuje transfer metil grupa sa metanola na metanol-specifični korinoidni protein (MtaC), učestvuje u metanogenezi koristeći metanol.

Reference

  1. van der Meijden, P., te Brömmelstroet, B.W., Poirot, C.M., van der Drift, C. and Vogels, G.D. (1984). „Purification and properties of methanol:5-hydroxybenzimidazolylcobamide methyltransferase from Methanosarcina barkeri. J. Bacteriol. 160: 629-635. PMID 6438059. 
  2. Sauer, K. and Thauer, R.K. (1999). „Methanol:coenzyme M methyltransferase from Methanosarcina barkeri – substitution of the corrinoid harbouring subunit MtaC by free cob(I)alamin”. Eur. J. Biochem. 261: 674-681. PMID 10215883. 

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