Meprin B

Meprin B
Identifikatori
EC broj 3.4.24.63
CAS broj 150679-52-0
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Meprin B (EC 3.4.24.63, meprin-b) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Hidroliza proteina, uključujući azokazein, i peptide. Hidroliza -His5-Leu-, -Leu6-Cys-, -Ala14-Leu- i -Cys19-Gly- veza u lancu insulina B

Ovaj enzim je prisutan u crevima miša.

Reference

  1. ↑ Kounnas, M.Z., Wolz, R.L., Gorbea, C.M. and Bond, J.S. (1991). „Meprin-A and -B. Cell surface endopeptidases of the mouse kidney”. J. Biol. Chem. 266: 17350-17357. PMID 1894622. 
  2. ↑ Gorbea, C.M., Marchand, P., Jiang, W., Copeland, N.G., Gilbert, D.J., Jenkins, N.A. and Bond, J.S. (1993). „Cloning, expression, and chromosomal localization of the mouse meprin β subunit”. J. Biol. Chem. 268: 21035-21043. PMID 8407940. 
  3. ↑ Johnson, G.D. and Hersh, L.B. (1994). „Expression of meprin subunit precursors. Membrane anchoring through the β subunit and mechanism of zymogen activation”. J. Biol. Chem. 269: 7682-7688. PMID 7510289. 
  4. ↑ Wolz, R.L. and Bond, J.S. (1995). „Meprins A and B”. Methods Enzymol. 248: 325-345. PMID 7674930. 

Literatura

Vanjske veze