Kvercetin 3-O-metiltransferaza

Kvercetin 3-O-metiltransferaza
Identifikatori
EC broj 2.1.1.76
CAS broj 81295-55-8
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Kvercetin 3-O-metiltransferaza (EC 2.1.1.76, flavonolna 3-O-metiltransferaza, flavonoidna 3-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:3,5,7,3',4'-pentahidroksiflavon 3-O-metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + 3,5,7,3',4'-pentahidroksiflavon S-adenozil-L-homocistein + 3-metoksi-5,7,3',4'-tetrahidroksiflavon

Ovaj enzim je specifičan za kvercetin.

Reference

  1. De Luca, V., Brunet, G., Khouri, H., Ibrahim, R. and Hrazdina, G. (1982). „Flavonol 3-O-methyltransferase in plant-tissues”. Z. Naturforsch. 37: 134-135. 
  2. De Luca, V. and Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 596-605. PMID 3994393. 
  3. De Luca, V. and Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 606-618. PMID 3994394. 
  4. Ibrahim, R.K. and De Luca, V. (1982). „Polymethylated flavonol synthesis is catalyzed by distinct O-methyltransferases”. Naturwissenschaften 69: 41-42. 

Literatura

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