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Katepsin e
Identifikatori
EC broj	3.4.23.34
CAS broj	110910-42-4
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Katepsin e (EC 3.4.23.34, proteinaza sporog kretanja, eritrocitna membranska aspartinska proteinaza, SMP, eritrocitna membranska aspartinska proteinaza, EMAP, nepepsinska proteinaza, katepsin D-slična kiselinska proteinaza, katepsinska E-slična kiselinska proteinaza, katepsinska D-tip proteinaza) je enzim.^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Aktivnost slična katepsinu D, sa malo širom specifičnošću

Ovaj enzim je prisutan u stomaku želucu, slezini i eritrocitnim membranama.

Reference

↑ Lapresle, C., Puizdar, V., Porchon-Bertolotto, C., Joukoff, E. and Turk, V. (1986). „Structural differences between rabbit cathepsin E and cathepsin D”. Biol. Chem. Hoppe-Seyler 367: 523-526. PMID 3741628.
↑ Yonezawa, S., Fujii, K., Maejima, Y., Tamoto, K., Mori, Y. and Muto, N. (1988). „Further studies on rat cathepsin E: subcellular localization and existence of the active subunit form”. Arch. Biochem. Biophys. 267: 176-183. PMID 3058036.
↑ Jupp, R.A., Richards, A.D., Kay, J., Dunn, B.M., Wyckoff, J.B., Samloff, I.M. and Yamamoto, K. (1988). „Identification of the aspartic proteinases from human erythrocyte membranes and gastric mucosa (slow-moving proteinase) as catalytically equivalent to cathepsin E”. Biochem. J. 254: 895-898. PMID 3058118.
↑ Azuma, T., Pals, G., Mohandas, T.K., Couvreur, J.M. and Taggart, R.T. (1989). „Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases”. J. Biol. Chem. 264: 16748-16753. PMID 2674141.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Cathepsin+E

[1] Lapresle, C., Puizdar, V., Porchon-Bertolotto, C., Joukoff, E. and Turk, V. (1986). „Structural differences between rabbit cathepsin E and cathepsin D”. Biol. Chem. Hoppe-Seyler 367: 523-526. PMID 3741628.

[2] Yonezawa, S., Fujii, K., Maejima, Y., Tamoto, K., Mori, Y. and Muto, N. (1988). „Further studies on rat cathepsin E: subcellular localization and existence of the active subunit form”. Arch. Biochem. Biophys. 267: 176-183. PMID 3058036.

[3] Jupp, R.A., Richards, A.D., Kay, J., Dunn, B.M., Wyckoff, J.B., Samloff, I.M. and Yamamoto, K. (1988). „Identification of the aspartic proteinases from human erythrocyte membranes and gastric mucosa (slow-moving proteinase) as catalytically equivalent to cathepsin E”. Biochem. J. 254: 895-898. PMID 3058118.

[4] Azuma, T., Pals, G., Mohandas, T.K., Couvreur, J.M. and Taggart, R.T. (1989). „Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases”. J. Biol. Chem. 264: 16748-16753. PMID 2674141.

[1]

[2]

[3]

[4]

Katepsin E

Reference

Literatura

Vanjske veze