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IgA-specifična metaloendopeptidaza
Identifikatori
EC broj	3.4.24.13
CAS broj	72231-73-3
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

IgA-specifična metaloendopeptidaza (EC 3.4.24.13, proteinaza imunoglobulina A1, IgA proteaza, IgA1-specifična proteinaza, IgA1 proteaza, IgA1 proteinaza) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Razlaganje Pro-Thr veze na regionu šarke teškog lanca ljudskog IgA

Ovaj enzim je prisutan u nekoliko patogenih vrsta Streptococcus.

Reference

↑ Kornfeld, S.J. and Plaut, A.G. (1981). „Secretory immunity and the bacterial IgA proteases”. Rev. Infect. Dis. 3: 521-534. PMID 6792682.
↑ Gilbert, J.V., Plaut, A.G. and Wright, A. (1991). „Analysis of the immunoglobulin A protease gene of Streptococcus sanguis”. Infect. Immun. 59: 7-17. PMID 1987065.
↑ Gilbert, J.V., Plaut, A.G., Fishman, Y. and Wright, A. (1988). „Cloning of the gene encoding streptococcal immunoglobulin A protease and its expression in Escherichia coli”. Infect. Immun. 56: 1961-1966. PMID 3294181.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH IgA-specific+metalloendopeptidase

[1] Kornfeld, S.J. and Plaut, A.G. (1981). „Secretory immunity and the bacterial IgA proteases”. Rev. Infect. Dis. 3: 521-534. PMID 6792682.

[2] Gilbert, J.V., Plaut, A.G. and Wright, A. (1991). „Analysis of the immunoglobulin A protease gene of Streptococcus sanguis”. Infect. Immun. 59: 7-17. PMID 1987065.

[3] Gilbert, J.V., Plaut, A.G., Fishman, Y. and Wright, A. (1988). „Cloning of the gene encoding streptococcal immunoglobulin A protease and its expression in Escherichia coli”. Infect. Immun. 56: 1961-1966. PMID 3294181.

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