Hepsin

Hepsin
Identifikatori
EC broj 3.4.21.106
CAS broj 112398-23-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Hepsin (EC 3.4.21.106) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Razlaganje nakon baznih aminokiselinskih ostataka, sa jakom preferencijom za Arg u odnosu na Lys

Ova membrana serinska peptidaza učestvuje u ćelijskom rastu i razvoju.

Reference

  1. ↑ Zhukov, A., Hellman, U. and Ingelman-Sundberg, M. (1997). „Purification and characterization of hepsin from rat liver microsomes”. Biochim. Biophys. Acta 1337: 85-95. PMID 9003440. 
  2. ↑ Kazama, Y., Hamamoto, T., Foster, D.C. and Kisiel, W. (1995). „Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation”. J. Biol. Chem. 270: 66-72. PMID 7814421. 
  3. ↑ Torres-Rosado, A., O'Shea, K.S., Tsuji, A., Chou, S.H. and Kurachi, K. (1993). „Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth”. Proc. Natl. Acad. Sci. USA 90: 7181-7185. PMID 8346233. 

Literatura

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