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Glicerolna dehidrataza
Identifikatori
EC broj	4.2.1.30
CAS broj	9077-68-3
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Glicerolna dehidrataza (EC 4.2.1.30, glicerolna dehidraza, glicerolna hidrolijaza) je enzim sa sistematskim imenom glicerol hidrolijaza (formira 3-hidroksipropanal).^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

glicerol

\rightleftharpoons

3-hidroksipropanal + H₂O

Za dejstvo ovog enzima je neophodan kobamidni koenzim.

Reference

↑ Forage, R.G. and Foster, M.A. (1982). „Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B₁₂-dependent glycerol and diol dehydratases”. J. Bacteriol. 149: 413-419. PMID 7035429.
↑ Schneider, Z., Larsen, E.G., Jacobsen, G., Johnson, B.C. and Pawelkiewicz, J. (1970). „Purification and properties of glycerol dehydrase”. J. Biol. Chem. 245: 3388-3396. PMID 4989992.
↑ Schneider, Z. and Pawelkiewicz, J. (1966). „The properties of glycerol dehydratase isolated from Aerobacter aerogenes, and the properties of the apoenzyme subunits”. Acta Biochim. Pol. 13: 311-328. PMID 5962440.
↑ Smiley, K.L. and Sobolov, M. (1962). „A cobamide-requiring glycerol dehydrase from an acrolein-forming Lactobacillus”. Arch. Biochem. Biophys. 97: 538-543. PMID 14039344.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Glycerol+dehydratase

[1] Forage, R.G. and Foster, M.A. (1982). „Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B₁₂-dependent glycerol and diol dehydratases”. J. Bacteriol. 149: 413-419. PMID 7035429.

[2] Schneider, Z., Larsen, E.G., Jacobsen, G., Johnson, B.C. and Pawelkiewicz, J. (1970). „Purification and properties of glycerol dehydrase”. J. Biol. Chem. 245: 3388-3396. PMID 4989992.

[3] Schneider, Z. and Pawelkiewicz, J. (1966). „The properties of glycerol dehydratase isolated from Aerobacter aerogenes, and the properties of the apoenzyme subunits”. Acta Biochim. Pol. 13: 311-328. PMID 5962440.

[4] Smiley, K.L. and Sobolov, M. (1962). „A cobamide-requiring glycerol dehydrase from an acrolein-forming Lactobacillus”. Arch. Biochem. Biophys. 97: 538-543. PMID 14039344.

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