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Gentisat 1,2-dioksigenaza
Identifikatori
EC broj	1.13.11.4
CAS broj	9029-48-5
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Gentisat 1,2-dioksigenaza (EC 1.13.11.4, gentisatna oksigenaza, 2,5-dihidroksibenzoatna dioksigenaza, gentisatna dioksigenaza, oksidaza gentisinske kiseline) je enzim sa sistematskim imenom gentisat:kiseonik 1,2-oksidoreduktaza (deciklizacija).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju:

2,5-dihidroksibenzoat + O₂

\rightleftharpoons

maleilpiruvat

Za rad ovog enzima neohodan je Fe^2+.

Reference

↑ Hayaishi, O. (1963). „Direct oxygenation by O₂, oxygenases”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 8 (2nd izd.). New York: Academic Press. str. 353-371.
↑ Sugiyama, S., Yano, K., Komagata, K. and Arima, K. (1960). „Metabolites of aromatic compounds by microbes. Part VII. Gentisic acid oxidase”. Bull. Agric. Chem. Soc. Jpn 24: 243-248.
↑ Sugiyama, S., Yano, K. and Arima, K. (1960). „Metabolites of aromatic compounds by microbes. Part VII. Further studies of gentisic acid oxidase”. Bull. Agric. Chem. Soc. Jpn 24: 249-254.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Hayaishi, O. (1963). „Direct oxygenation by O₂, oxygenases”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 8 (2nd izd.). New York: Academic Press. str. 353-371.

Vanjske veze

MeSH Gentisate+1,2-dioxygenase

[1] Hayaishi, O. (1963). „Direct oxygenation by O₂, oxygenases”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 8 (2nd izd.). New York: Academic Press. str. 353-371.

[2] Sugiyama, S., Yano, K., Komagata, K. and Arima, K. (1960). „Metabolites of aromatic compounds by microbes. Part VII. Gentisic acid oxidase”. Bull. Agric. Chem. Soc. Jpn 24: 243-248.

[3] Sugiyama, S., Yano, K. and Arima, K. (1960). „Metabolites of aromatic compounds by microbes. Part VII. Further studies of gentisic acid oxidase”. Bull. Agric. Chem. Soc. Jpn 24: 249-254.

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