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Estradiol 6b-monooksigenaza
Identifikatori
EC broj	1.14.99.11
CAS broj	9029-70-3
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Estradiol 6b-monooksigenaza (EC 1.14.99.11, estradiolna 6beta-hidroksilaza) je enzim sa sistematskim imenom estradiol-17beta,vodonik-donor:kiseonik oksidoreduktaza (6beta-hidroksilacija).^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

estradiol-17beta + AH₂ + O₂

\rightleftharpoons

6beta-hidroksiestradiol-17beta + A + H₂O

Reference

↑ Haines, W.J. (1952). „The biosynthesis of adrenal cortex hormones”. Recent Progr. Hormone Res. 7: 255-305.
↑ Mueller, G.C. and Rumney, G. (1957). „Formation of 6β-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes”. J. Am. Chem. Soc. 79: 1004-1005.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Estradiol+6beta-monooxygenase

[1] Haines, W.J. (1952). „The biosynthesis of adrenal cortex hormones”. Recent Progr. Hormone Res. 7: 255-305.

[2] Mueller, G.C. and Rumney, G. (1957). „Formation of 6β-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes”. J. Am. Chem. Soc. 79: 1004-1005.

[1]

[2]