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Epoksidna hidrolaza
	Epoksidna hidrolaza 2, dimer, Human
Identifikatori
EC broj	3.3.2.3
CAS broj	9048-63-9
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Epoksidna hidrolaza (EC 3.3.2.3, epoksidna hidrataza, aren-oksidna hidrataza, benzo(a)piren-4,5-oksidna hidrataza, benzo(a)piren-4,5-epoksidna hidrataza, aril epoksidna hidraza, cis-epoksidna hidrolaza, trans-stilbensko oksidna hidrolaza, ksenobiotsko epoksidna hidrolaza) je enzim sa sistematskim imenom epoksidna hidrolaza.^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

epoksid + H₂O

\rightleftharpoons

glikol

Ovaj enzim deluje na mnoštvo epoksidnih i arenskih oksida.

Reference

↑ Jakoby, W.B. and Fjellstedt, T.A. (1972). „Epoxidases”. u: Boyer, P.D.. The Enzymes. 7 (3rd izd.). New York: Academic Press. str. 199-212.
↑ Lu, A.Y.H., Ryan, D., Jerina, D.M., Daly, J.W. and Levin, W. (1975). „Liver microsomal epoxide hydrase. Solubilization, purification, and characterization”. J. Biol. Chem. 250: 8283-8288.
↑ Oesch, F. (1974). „Purification and specificity of a human microsomal epoxide hydratase”. Biochem. J. 139: 77-88. PMID 4463951.
↑ Oesch, F. and Daly, J. (1971). „Solubilization, purification, and properties of a hepatic epoxide hydrase”. Biochim. Biophys. Acta 227: 692-697. PMID 4998715.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Jakoby, W.B. and Fjellstedt, T.A. (1972). „Epoxidases”. u: Boyer, P.D.. The Enzymes. 7 (3rd izd.). New York: Academic Press. str. 199-212.

Vanjske veze

MeSH Epoxide+hydrolase

[1] Jakoby, W.B. and Fjellstedt, T.A. (1972). „Epoxidases”. u: Boyer, P.D.. The Enzymes. 7 (3rd izd.). New York: Academic Press. str. 199-212.

[2] Lu, A.Y.H., Ryan, D., Jerina, D.M., Daly, J.W. and Levin, W. (1975). „Liver microsomal epoxide hydrase. Solubilization, purification, and characterization”. J. Biol. Chem. 250: 8283-8288.

[3] Oesch, F. (1974). „Purification and specificity of a human microsomal epoxide hydratase”. Biochem. J. 139: 77-88. PMID 4463951.

[4] Oesch, F. and Daly, J. (1971). „Solubilization, purification, and properties of a hepatic epoxide hydrase”. Biochim. Biophys. Acta 227: 692-697. PMID 4998715.

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