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Endopeptidaza K
Identifikatori
EC broj	3.4.21.64
CAS broj	39450-01-6
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Endopeptidaza K (EC 3.4.21.64, Tritirachium alkaline proteinaza, Tritirachium album serin proteinaza, proteinaza K, Tritirachium album proteinaza K) je enzim.^[1]^[2]^[3]^[4]^[5] Ovaj enzim katalizuje sledeću hemijsku reakciju

Hidroliza keratina, i drugih proteina sa subtilisinu sličnom specifičnošću. Dolazi do hidrolize peptidnih amida

Ovaj enzim je izolovan iz plesni Tritirachium album Limber.

Reference

↑ Ebeling, W., Hennrich, N., Klockow, M., Metz, H., Orth, H.D. and Lang, H. (1974). „Proteinase K from Tritirachium album Limber”. Eur. J. Biochem. 47: 91-97. PMID 4373242.
↑ Morihara, K. and Tsuzuki, H. (1975). „Specificity of proteinase K from Tritirachium album Limber for synthetic peptides”. Agric. Biol. Chem. 39: 1489-1492.
↑ Kraus, E., Klitz, H.H. and Fembert, U.F. (1976). „The specificity of proteinase K against oxidized insulin B chain”. Hoppe-Seyler's Z. Physiol. Chem. 357: 233-237. PMID 943367.
↑ Jany, K.-D., Lederer, G. and Mayer, B. (1986). „Amino acid sequence of proteinase K from the mold Tritirachium album Limber”. FEBS Lett. 199: 139-144.
↑ Betzel, C., Teplyakov, A.V., Harutyunyan, E.H., Saenger, W. and Wilson, K.S. (1990). „Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes”. Protein Engineering 3: 161-172. PMID 2184432.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Peptidase+K

[1] Ebeling, W., Hennrich, N., Klockow, M., Metz, H., Orth, H.D. and Lang, H. (1974). „Proteinase K from Tritirachium album Limber”. Eur. J. Biochem. 47: 91-97. PMID 4373242.

[2] Morihara, K. and Tsuzuki, H. (1975). „Specificity of proteinase K from Tritirachium album Limber for synthetic peptides”. Agric. Biol. Chem. 39: 1489-1492.

[3] Kraus, E., Klitz, H.H. and Fembert, U.F. (1976). „The specificity of proteinase K against oxidized insulin B chain”. Hoppe-Seyler's Z. Physiol. Chem. 357: 233-237. PMID 943367.

[4] Jany, K.-D., Lederer, G. and Mayer, B. (1986). „Amino acid sequence of proteinase K from the mold Tritirachium album Limber”. FEBS Lett. 199: 139-144.

[5] Betzel, C., Teplyakov, A.V., Harutyunyan, E.H., Saenger, W. and Wilson, K.S. (1990). „Thermitase and proteinase K: a comparison of the refined three-dimensional structures of the native enzymes”. Protein Engineering 3: 161-172. PMID 2184432.

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