Dolihil-fosfat b-D-manoziltransferaza

Dolihil-fosfat b-D-manoziltransferaza
Identifikatori
EC broj 2.4.1.83
CAS broj 62213-44-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Dolihil-fosfat b-D-manoziltransferaza (EC 2.4.1.83, GDP-Man:DolP manoziltransferaza, dolihil manozil fosfat sintaza, dolihil-fosfo-manoza sintaza, GDP-manoza:dolihil-fosfat manoziltransferaza, guanozin difosfomanoza-dolihol fosfat manoziltransferaza, dolihol fosfat manozna sintaza, dolihil fosfatna manoziltransferaza, dolihil-fosfat manozna sintaza, GDP-manoza-dolihol fosfatna manoziltransferaza, GDP-manoza-dolihilmonofosfatna manoziltransferaza, manozilfosfodoliholna sintaza, manozilfosforildolihol sintaza) je enzim sa sistematskim imenom GDP-manoza:dolihil-fosfat beta-D-manoziltransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

GDP-manoza + dolihil fosfat GDP + dolihil D-manozil fosfat

Ovaj enzim deluje samo na dugolančane poliprenil fosfate i alfa-dihidropoliprenil fosfate koji su suži od C35.

Reference

  1. ↑ Babczinski, P., Haselbeck, A. and Tanner, W. (1980). „Yeast mannosyl transferases requiring dolichyl phosphate and dolichyl phosphate mannose as substrate. Partial purification and characterization of the solubilized enzyme”. Eur. J. Biochem. 105: 509-515. PMID 6989607. 
  2. ↑ Bretthauer, R.K., Wu, S. and Irwin, W.E. (1973). „Enzymatic transfer of mannose from guanosine diphosphate mannose to dolichol phosphate in yeast (Hansenula holstii). A possible step in mannan synthesis”. Biochim. Biophys. Acta 304: 736-747. PMID 4726855. 
  3. ↑ Haselbeck, A. (1989). „Purification of GDP mannose:dolichyl-phosphate O-β-D-mannosyltransferase from Saccharomyces cerevisiae”. Eur. J. Biochem. 181: 663-668. PMID 2659345. 
  4. ↑ Palamarczyk, G., Lehle, L., Mankowski, T., Chojnacki, T. and Tanner, W. (1980). „Specificity of solubilized yeast glycosyl transferases for polyprenyl derivatives”. Eur. J. Biochem. 105: 517-523. PMID 6445267. 
  5. ↑ Richards, J.B. and Hemming, F.W. (1972). „The transfer of mannose from guanosine diphosphate mannose to dolichol phosphate and protein by pig liver endoplasmic reticulum”. Biochem. J. 130: 77-93. PMID 4655455. 

Literatura

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