PROFILPELAJAR.COM

Dipeptidilna peptidaza III
Identifikatori
EC broj	3.4.14.4
CAS broj	77464-87-0
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Dipeptidilna peptidaza III (EC 3.4.14.4, dipeptidil aminopeptidaza III, dipeptidil arilamidaza III, enkefalinaza B, angiotenzinaza crvenih ćelija) je enzim.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Odvajanje N-terminalnog dipeptida sa peptida koji sadrži četiri ili više ostataka, sa širokom specifičnošću. Takođe deluje na dipeptidil 2-naftilamide.

Ova citozolna peptidaza je aktivna pri neutralnom pH.

Reference

↑ McDonald, J.K. (1998). „Dipeptidyl-peptidase III”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 536-538.
↑ Fukasawa, K., Fukasawa, K.M., Iwamoto, H., Hirose, J. and Harada, M. (1999). „The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme”. Biochemistry 38: 8299-8303. PMID 10387075.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

McDonald, J.K. (1998). „Dipeptidyl-peptidase III”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 536-538.

Vanjske veze

MeSH Dipeptidyl-peptidase+III

[1] McDonald, J.K. (1998). „Dipeptidyl-peptidase III”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. str. 536-538.

[2] Fukasawa, K., Fukasawa, K.M., Iwamoto, H., Hirose, J. and Harada, M. (1999). „The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme”. Biochemistry 38: 8299-8303. PMID 10387075.

[1]

[2]