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Dezoksiuridin fosforilaza
Identifikatori
EC broj	2.4.2.23
CAS broj	37277-77-3
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Dezoksiuridin fosforilaza (EC 2.4.2.23, Deoxyuridine phosphorylase) je enzim sa sistematskim imenom 2'-dezoksiuridin:fosfat 2-dezoksi-alfa-D-riboziltransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

2'-dezoksiuridin + fosfat

\rightleftharpoons

uracil + 2-dezoksi-alfa-D-riboza 1-fosfat

Reference

↑ Cihák, A. and Sorm, F. (1964). „Inhibition by 5-azauracil of the uridine phosphorylase and deoxyuridine phosphorylase activities in a cell-free extract of mouse liver”. Biochim. Biophys. Acta 80: 672-674. PMID 14156740.
↑ Yamada, E.W. (1964). „The effect of cortisol administration on the activities of uridine and deoxyuridine phosphorylases of normal and regenerating rat liver”. Can. J. Biochem. 42: 317-325.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Deoxyuridine+phosphorylase

[1] Cihák, A. and Sorm, F. (1964). „Inhibition by 5-azauracil of the uridine phosphorylase and deoxyuridine phosphorylase activities in a cell-free extract of mouse liver”. Biochim. Biophys. Acta 80: 672-674. PMID 14156740.

[2] Yamada, E.W. (1964). „The effect of cortisol administration on the activities of uridine and deoxyuridine phosphorylases of normal and regenerating rat liver”. Can. J. Biochem. 42: 317-325.

[1]

[2]