Demetilmenahinon metiltransferaza

Demetilmenahinon metiltransferaza
Identifikatori
EC broj 2.1.1.163
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Demetilmenahinon metiltransferaza (EC 2.1.1.163, S-adenozil-L-metion---DMK metiltransferaza, demetilmenahinon C-metilaza, 2-heptaprenil-1,4-naftohinon metiltransferaza, 2-demetilmenahinon metiltransferaza, S-adenozil-L-metion:2-demetilmenahinon metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metion:demetilmenahinon metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

demetilmenahinol + S-adenozil-L-metionin menahinol + S-adenozil-L-homocistein

Ovaj enzim katalizuje zadnji korak menahinonske biosinteza.

Reference

  1. ↑ Koike-Takeshita, A., Koyama, T. and Ogura, K. (1997). „Identification of a novel gene cluster participating in menaquinone (vitamin K2) biosynthesis. Cloning and sequence determination of the 2-heptaprenyl-1,4-naphthoquinone methyltransferase gene of Bacillus stearothermophilus”. J. Biol. Chem. 272: 12380-12383. PMID 9139683. 
  2. ↑ Wissenbach, U., Ternes, D. and Unden, G. (1992). „An Escherichia coli mutant containing only demethylmenaquinone, but no menaquinone: effects on fumarate, dimethylsulfoxide, trimethylamine N-oxide and nitrate respiration”. Arch. Microbiol. 158: 68-73. PMID 1444716. 
  3. ↑ Catala, F., Azerad, R. and Lederer, E. (1970). „Sur les propriétés de la desméthylménaquinone C-méthylase de Mycobacterium phlei”. Int. Z. Vitaminforsch. 40: 363-373. PMID 5450997. 
  4. ↑ Lee, P.T., Hsu, A.Y., Ha, H.T. and Clarke, C.F. (1997). „A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene”. J. Bacteriol. 179: 1748-1754. PMID 9045837. 

Literatura

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