Citozol-alanilna aminopeptidaza

Citozol-alanilna aminopeptidaza
Identifikatori
EC broj 3.4.11.14
CAS broj 243859-94-1
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Citozol-alanilna aminopeptidaza (EC 3.4.11.14, arilamidaza, aminopolipeptidaza, tiol-aktivirana aminopeptidaza, aminopeptidaza ljudske jetre, puromicin-senzitivna aminopeptidaza, aminopeptidaza rastvornog alanila, citosolna aminopeptidaza III, alaninska aminopeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Odvajanje N-terminalne aminokiseline, preferentno alanina, sa širokog opsega peptida, amida i arilamida

Ovaj enzim je senzitivan na puromicin. Za njegov rad je neophodan jon Co2+.

Reference

  1. Starnes, W.L. and Behal, F.J. (1974). „A human liver aminopeptidase. The amino acid and carbohydrate content, and some physical properties of a sialic acid containing glycoprotein”. Biochemistry 13: 3221-3227. PMID 4841062. 
  2. Kao, Y.J., Starnes, W.L. and Behal, F.J. (1978). „Human kidney alanine aminopeptidase: physical and kinetic properties of a sialic acid containing glycoprotein”. Biochemistry 17: 2990-2994. PMID 698181. 
  3. Sidorowicz, W., Hsia, W.-C., Maslej-Zownir, M. and Behal, F.J. (1980). „Multiple molecular forms of human alanine aminopeptidase: imunochemical properties”. Clin. Chim. Acta 107: 245-256. PMID 6108169. 

Literatura

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