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Koatomerni proteinski kompleks, podjedinica gama 2
Identifikatori
Simboli	COPG2; 2-COP; DKFZp761N09121; FLJ11781
Vanjski ID	OMIM: 604355 HomoloGene: 56292 GeneCards: COPG2 Gene
Ontologija gena
Molekularna funkcija	• aktivnost strukturnog molekula; • proteinsko vezivanje;
Celularna komponenta	• Goldžijeva membrana; • citoplazma; • Goldžijev aparat; • membrana; • membranski pokrivač; • pokrivač COPI vezikule; • citoplazmatična vetikula;
Biološki proces	• intracelularni proteinski transport; • retrogradni vezikulom posredovani transport, Goldži do ER; • intra-Goldžijev vezikulom posredovani transport; • vezikulom posredovani transport;
Ortolozi

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Koatomerna podjedinica gama-2 je protein koji je kod ljudi kodiran COPG2 genom.^[1]^[2]^[3]

Interakcije

Za COPG2 je pokazano da formira interakcije sa dopaminskim receptorom D1^[4] i COPB1.^[5]^[6]

Izvori

↑ Blagitko N, Schulz U, Schinzel AA, Ropers HH, Kalscheuer VM (Jan 2000). „gamma2-COP, a novel imprinted gene on chromosome 7q32, defines a new imprinting cluster in the human genome”. Hum Mol Genet 8 (13): 2387–96. DOI:10.1093/hmg/8.13.2387. PMID 10556286.
↑ Yamasaki K, Hayashida S, Miura K, Masuzaki H, Ishimaru T, Niikawa N, Kishino T (Nov 2000). „The novel gene, gamma2-COP (COPG2), in the 7q32 imprinted domain escapes genomic imprinting”. Genomics 68 (3): 330–5. DOI:10.1006/geno.2000.6265. PMID 10995575.
↑ „Entrez Gene: COPG2 coatomer protein complex, subunit gamma 2”.
↑ Bermak, Jason C; Li Ming, Bullock Clayton, Weingarten Paul, Zhou Qun-Yong (February 2002). „Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus”. Eur. J. Cell Biol. (Germany) 81 (2): 77–85. DOI:10.1078/0171-9335-00222. ISSN 0171-9335. PMID 11893085.
↑ Takatsu, H; Futatsumori M, Yoshino K, Yoshida Y, Shin H W, Nakayama K (June 2001). „Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system”. Biochem. Biophys. Res. Commun. (United States) 284 (4): 1083–9. DOI:10.1006/bbrc.2001.5081. ISSN 0006-291X. PMID 11409905.
↑ Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (2000). „Identification and characterization of novel isoforms of COP I subunits.”. J Biochem 128 (5): 793–801. PMID 11056392.

Literatura

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Lowe M, Kreis TE (1997). „In vivo assembly of coatomer, the COP-I coat precursor.”. J. Biol. Chem. 271 (48): 30725–30. DOI:10.1074/jbc.271.48.30725. PMID 8940050.
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