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Alfa-farnezenska sintaza
Identifikatori
EC broj	4.2.3.46
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Alfa-farnezenska sintaza (EC 4.2.3.46, (E,E)-alfa-farnezen sintaza, AFS1, MdAFS1) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat lijaza (formira (3E,6E)-alfa-farnezen).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

(2E,6E)-farnezil difosfat

\rightleftharpoons

(3E,6E)-alfa-farnezen + difosfat

Reference

↑ Pechous, S.W. and Whitaker, B.D. (2004). „Cloning and functional expression of an (E,E)-α-farnesene synthase cDNA from peel tissue of apple fruit”. Planta 219: 84-94. PMID 14740213.
↑ Green, S., Squire, C.J., Nieuwenhuizen, N.J., Baker, E.N. and Laing, W. (2009). „Defining the potassium binding region in an apple terpene synthase”. J. Biol. Chem. 284: 8661-8669. PMID 19181671.
↑ Nieuwenhuizen, N.J., Wang, M.Y., Matich, A.J., Green, S.A., Chen, X., Yauk, Y.K., Beuning, L.L., Nagegowda, D.A., Dudareva, N. and Atkinson, R.G. (2009). „Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa)”. J. Exp. Bot. 60: 3203-3219. PMID 19516075.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH Alpha-farnesene+synthase

[1] Pechous, S.W. and Whitaker, B.D. (2004). „Cloning and functional expression of an (E,E)-α-farnesene synthase cDNA from peel tissue of apple fruit”. Planta 219: 84-94. PMID 14740213.

[2] Green, S., Squire, C.J., Nieuwenhuizen, N.J., Baker, E.N. and Laing, W. (2009). „Defining the potassium binding region in an apple terpene synthase”. J. Biol. Chem. 284: 8661-8669. PMID 19181671.

[3] Nieuwenhuizen, N.J., Wang, M.Y., Matich, A.J., Green, S.A., Chen, X., Yauk, Y.K., Beuning, L.L., Nagegowda, D.A., Dudareva, N. and Atkinson, R.G. (2009). „Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa)”. J. Exp. Bot. 60: 3203-3219. PMID 19516075.

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