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23S rRNK pseudouridinska2605 sintaza
Identifikatori
EC broj	5.4.99.22
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

23S rRNK pseudouridinska²⁶⁰⁵ sintaza (EC 5.4.99.22, RluB, YciL) je enzim sa sistematskim imenom 23S rRNK-uridin²⁶⁰⁵ uracil mutaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

23S rRNK uridin²⁶⁰⁵

\rightleftharpoons

23S rRNK pseudouridin²⁶⁰⁵

Pseudouridinska sintaza RluB konvertuje uridin²⁶⁰⁵ molekula 23S rRNK do pseudouridina.

Reference

↑ Del Campo, M., Kaya, Y. and Ofengand, J. (2001). „Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli”. RNA 7: 1603-1615. PMID 11720289.
↑ Jiang, M., Sullivan, S.M., Walker, A.K., Strahler, J.R., Andrews, P.C. and Maddock, J.R. (2007). „Identification of novel Escherichia coli ribosome-associated proteins using isobaric tags and multidimensional protein identification techniques”. J. Bacteriol. 189: 3434-3444. PMID 17337586.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH 23S+rRNA+pseudouridine2605+synthase

[1] Del Campo, M., Kaya, Y. and Ofengand, J. (2001). „Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli”. RNA 7: 1603-1615. PMID 11720289.

[2] Jiang, M., Sullivan, S.M., Walker, A.K., Strahler, J.R., Andrews, P.C. and Maddock, J.R. (2007). „Identification of novel Escherichia coli ribosome-associated proteins using isobaric tags and multidimensional protein identification techniques”. J. Bacteriol. 189: 3434-3444. PMID 17337586.

[1]

[2]

23S rRNK pseudouridinska2605 sintaza

Reference

Literatura

Vanjske veze