2',3'-Ciklični-nukleotid 2'-fosfodiestaraza

2',3'-Ciklični-nukleotid 2'-fosfodiestaraza
Identifikatori
EC broj 3.1.4.16
CAS broj 9037-18-7
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

2',3'-Ciklični-nukleotid 2'-fosfodiestaraza (EC 3.1.4.16, ribonukleozid 2',3'-ciklična fosfat diesteraza, 2',3 '-ciklična AMP fosfodiesteraza, 2',3'-ciklična nukleotidaza, ciklična 2',3'-nukleotid 2'-fosfodiesteraza, ciklična 2',3'-nukleotid fosfodiesteraza, 2',3'-ciklična nukleozid monofosfat fosfodiesteraza, 2',3'-ciklična AMP 2'-fosfohidrolaza, ciklična fosfodiesteraza:3'-nukleotidaza, 2',3'-ciklična nukleotid fosfohidrolaza, 2':3'-ciklična fosfodiesteraza, 2':3'-ciklična nukleotid fosfodiesteraza:3'-nukleotidaza) je enzim sa sistematskim imenom nukleozid-2',3'-ciklična-fosfat 3'-nukleotidohidrolaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

nukleozid 2',3'-ciklični fosfat + H2O nukleozid 3'-fosfat

Ovaj enzim takođe hidrolizuje 3'-nukleozid monofosfate i bis-4-nitrofenil fosfate.

Reference

  1. ↑ Anraku, Y. (1964). „A new cyclic phosphodiesterase having a 3′-nucleotidase activity from Escherichia coli B. I. Purification and some properties of the enzyme”. J. Biol. Chem. 239: 3412-3419. PMID 14245396. 
  2. ↑ Anraku, Y. (1964). „A new cyclic phosphodiesterase having a 3′-nucleotidase activity from Escherichia coli B. II. Further studies on substrate specificity and mode of action of the enzyme”. J. Biol. Chem. 239: 3420-3424. PMID 14245397. 
  3. ↑ Center, M.S. and Behal, F.J. (1968). „A cyclic phosphodiesterase with 3′-nucleotidase activity from Proteus mirabilis”. J. Biol. Chem. 243: 138-143. PMID 4295113. 
  4. ↑ Olafson, R.W., Drummond, G.I. and Lee, J.F. (1969). „Studies on 2′,3′-cyclic nucleotide-3′-phosphohydrolase from brain”. Can. J. Biochem. 47: 961-966. PMID 4310670. 
  5. ↑ Unemoto, T. and Hayashi, M. (1969). „Chloride ion as a modifier of 2′,3′-cyclic phosphodiesterase purified from halophilic Vibrio alginolyticus”. Biochim. Biophys. Acta 171: 89-102. PMID 4303200. 

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