PROFILPELAJAR.COM

16S rRNK (citozin967-C5)-metiltransferaza
Identifikatori
EC broj	2.1.1.176
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

16S rRNK (citozin⁹⁶⁷-C⁵)-metiltransferaza (EC 2.1.1.176, rsmB (gen), fmu (gen), 16S rRNK m5C967 metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (citozin⁹⁶⁷-C⁵)-metiltransferaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + citozin⁹⁶⁷ u 16S rRNK

\rightleftharpoons

S-adenozil-L-homocistein + 5-metilcitozin⁹⁶⁷ u 16S rRNK

Ovaj enzim specifično metiliše citozin⁹⁶⁷ u C5 poziciji 16S rRNK.

Reference

↑ Tscherne, J.S., Nurse, K., Popienick, P., Michel, H., Sochacki, M. and Ofengand, J. (1999). „Purification, cloning, and characterization of the 16S RNA m⁵C⁹⁶⁷ methyltransferase from Escherichia coli”. Biochemistry 38: 1884-1892. PMID 10026269.
↑ Gu, X.R., Gustafsson, C., Ku, J., Yu, M. and Santi, D.V. (1999). „Identification of the 16S rRNA m⁵C⁹⁶⁷ methyltransferase from Escherichia coli”. Biochemistry 38: 4053-4057. PMID 10194318.
↑ Foster, P.G., Nunes, C.R., Greene, P., Moustakas, D. and Stroud, R.M. (2003). „The first structure of an RNA m⁵C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate”. Structure 11: 1609-1620. PMID 14656444.

Literatura

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

MeSH 16S+rRNA+(cytosine967-C5)-methyltransferase

[1] Tscherne, J.S., Nurse, K., Popienick, P., Michel, H., Sochacki, M. and Ofengand, J. (1999). „Purification, cloning, and characterization of the 16S RNA m⁵C⁹⁶⁷ methyltransferase from Escherichia coli”. Biochemistry 38: 1884-1892. PMID 10026269.

[2] Gu, X.R., Gustafsson, C., Ku, J., Yu, M. and Santi, D.V. (1999). „Identification of the 16S rRNA m⁵C⁹⁶⁷ methyltransferase from Escherichia coli”. Biochemistry 38: 4053-4057. PMID 10194318.

[3] Foster, P.G., Nunes, C.R., Greene, P., Moustakas, D. and Stroud, R.M. (2003). „The first structure of an RNA m⁵C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate”. Structure 11: 1609-1620. PMID 14656444.

[1]

[2]

[3]

16S rRNK (citozin967-C5)-metiltransferaza

Reference

Literatura

Vanjske veze