For advancing the field of chemical synthesis to the extremes of molecular complexity, linking structure and function and expanding our dominion over the interface of chemistry, biology and medicine

For pioneering chemical insights into the logic of signal transduction and gene regulation that led to important, new therapeutics, and for advancing chemical biology and medicine through the discovery of small-molecule probes

for pioneering reticular chemistry via metal-organic frameworks and covalent organic framework

for conceiving metal-directed assembly principles leading to large highly porous complexes

for the development of efficient transition-metal catalysts that have revolutionized drug manufacturing, leading to breakthrough in molecule and synthetics design.

for collaboratively established the fundamental reciprocal influences of three-dimensional molecular structure upon structures of organic crystals

for developing activity-based protein profiling, a chemical proteomic strategy, to characterize enzyme function in native biological systems, and describe numerous enzymes which play critical roles in human biology and disease, including the endocannabinoid hydrolases whose lipid products regulate communication between cells

for pioneering biorthogonal chemistry and understanding glycocalyx, and its roles in both health and disease, thus allowing for bioimaging, chemoproteomics, and in-vivo drug delivery

for her work elucidating the role of chemical communication between bacteria. She has made important discoveries revealing how quorum sensing is used by bacteria both for virulence and for communicating across species