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(a) SCF contains three core subunits—the RING protein Rbx1, the cullin Cul1, and Skp1. Rbx1 binds the E2–ubiquitin conjugate. The target protein binds to an F-box protein that is bound to the enzyme core via interactions with the Skp1 subunit. After binding of a target protein to the F-box protein, the ubiquitin is transferred from E2 and attached via a peptide bond to a lysine side chain in the target protein. (b) A composite model structure for human SCF derived from X-ray structures of...

Artery which supplies blood to the occipital lobe of the brain Posterior cerebral arteryThe outer surface of the human brain, with the area supplied by the posterior cerebral artery shown in yellow.The arterial circle and arteries of the brain (inferior view). The posterior cerebral arteries (bottom forks) arise from the basilar artery (center).DetailsSourcebasilar artery (most common in adults)Veincerebral veinsSuppliesoccipital lobe of cerebrumIdentifiersLatinarteria cerebri posteriorAcrony...

Heritage-listed theater in Sydney, Australia State TheatreFacade from Market StreetLocation47-51 Market Street, Sydney, City of Sydney, New South Wales, AustraliaCoordinates33°52′16″S 151°12′27″E / 33.8712°S 151.2074°E / -33.8712; 151.2074Built1926–1929ArchitectHenry Eli White, John EbersonOwnerEvent Hospitality and Entertainment; Claude Neon Pty Ltd New South Wales Heritage RegisterOfficial nameState Theatre; State Building; Wurlitzer OrganTypeState heri...

Topical glucocorticoid drug ChloroprednisoneClinical dataOther names6α-Chloro-1,4-pregnadiene-17a,21-diol-3,11,20-trioneATC codeS01CA09 (WHO) (combination with antiinfectives)Identifiers IUPAC name (6α)-6-Chloro-17,21-dihydroxypregna-1,4-diene-3,11,20-trione CAS Number52080-57-6PubChem CID3034026ChemSpider2298578UNII564IBO56IPECHA InfoCard100.052.387 Chemical and physical dataFormulaC21H25ClO5Molar mass392.88 g·mol−13D model (JSmol)Interactive image SMILES O=C(CO)[C@@]3(O)...

Kesultanan Jalayirid1335–1432StatusKekaisaranPemerintahanMonarkiSejarah • Didirikan 1335• Dibubarkan 1432 Didahului oleh Digantikan oleh Ilkhanate Kara Koyunlu Sunting kotak info • Lihat • BicaraBantuan penggunaan templat ini Bagian dari seri mengenai Sejarah Iran Mitos Sejarah Wangsa Pisydadi Wangsa Kayani Zaman Kuno SM Peradaban Kura-Aras 3400–2000 Proto-Elam 3200–2700 Elam 2700–539 Kekaisaran Akadia 2400–2150 Bangsa Kass ca.1500 – ca.1155 Kekais...

Christian Träsch Nazionalità  Germania Altezza 180 cm Peso 74 kg Calcio Ruolo Difensore Termine carriera 2020 Carriera Giovanili  Ingolstadt 042003-2006 Monaco 1860 Squadre di club1 2006-2007 Monaco 1860 II39 (2)2007-2008 Stoccarda II39 (1)2008-2011 Stoccarda83 (5)2011-2017 Wolfsburg126 (0)2017-2019 Ingolstadt 0435 (1)2020 Al-Wasl1 (0) Nazionale 2009-2011 Germania10 (0) 1 I due numeri indicano le presenze e le reti segnate, per le sole partite d...

Eurovision Song Contest 2022Country United KingdomNational selectionSelection processInternal selectionSelection date(s)10 March 2022Selected entrantSam RyderSelected songSpace ManSelected songwriter(s)Sam RyderAmy WadgeMax WolfgangFinals performanceFinal result2nd, 466 pointsUnited Kingdom in the Eurovision Song Contest ◄2021 • 2022 • 2023► The United Kingdom participated in the Eurovision Song Contest 2022 in Turin, Italy. British singer-songwrite...

Cleavage of chemical bonds by the addition of water Not to be confused with Hydrogenolysis, Hydroxylation, or Water splitting. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Hydrolysis – news · newspapers · books · scholar · JSTOR (January 2021) (Learn how and when to remove this template message) Generic h...

Il sistema scheletrico è l'insieme delle ossa, delle cartilagini e delle articolazioni del corpo di diversi animali. La cartilagine è un tessuto connettivo solido e flessibile, forma la gran parte dello scheletro di un bambino e, con la crescita, viene sostituita in gran parte dal tessuto osseo. Lo scheletro costituisce la struttura portante del corpo, ed è formato dall'insieme delle ossa, variamente unite tra di loro da formazioni dette articolazioni. Queste si possono classificare in 3 g...

この項目には、一部のコンピュータや閲覧ソフトで表示できない文字が含まれています（詳細）。 数字の大字（だいじ）は、漢数字の一種。通常用いる単純な字形の漢数字（小字）の代わりに同じ音の別の漢字を用いるものである。 概要 壱万円日本銀行券（「壱」が大字） 弐千円日本銀行券（「弐」が大字） 漢数字には「一」「二」「三」と続く小字と、「壱」「�...

Численность населения республики по данным Росстата составляет 4 003 016[1] чел. (2024). Татарстан занимает 8-е место по численности населения среди субъектов Российской Федерации[2]. Плотность населения — 59,00 чел./км² (2024). Городское население — 76,72[3] % (20...

Hasyim bin Abdul Manafهاشم ٱبن عبد منافPemimpin ke-3 suku QuraisyPendahuluAbdu Manaf bin QushayPenerusAbdul MuthalibInformasi pribadiKelahiranAmrc. 464MekkahKematianc. 497 (umur 32-33)PemakamanGaza, PalestinaAyahAbdu Manaf bin QushayIbuAtikah binti MurrahPasanganSiti Jenah binti Syeh mattab bin hisyamAnakAsad bin Hasyim Abdul MuthalibPekerjaanPengusaha Hasyim bin Abdu Manaf (Bahasa Arab: هاشم بن عبد مناف) (meninggal 497) adalah pendiri dari Bani Hasyim, dan buyut da...

Japanese professional wrestling tag team Professional wrestling tag team Saito Brothers Jun Saito and Rei SaitoTag teamMembersJun SaitoRei SaitoBilled heightsJun:1.93 m (6 ft 4 in)[1]Rei:1.92 m (6 ft 3+1⁄2 in)[2]Combinedbilled weightCombined: 559 lb (254 kg)255 lb (116 kg) (Jun)304 lb (138 kg) (Rei)[1][2]DebutJune 9, 2021[3][4]Years active2021–present The Saito Brothers are a pr...

Capital city of Alagoas, Brazil Municipality in Alagoas, BrazilMaceióMunicipalityMunicipality of MaceióFrom the top, clockwise: Aerialview of Maceió; Alagoas State Museum; Álvaro Otacílio Avenue; Pajuçara beach; Ipioca beach and Ponta Verde seen from above. FlagCoat of armsNickname: Brazilian CaribbeanLocation of Maceió in the State of AlagoasMaceióLocation in BrazilCoordinates: 9°39′57″S 35°44′06″W / 9.66583°S 35.73500°W / -9.66583; -35.73500C...

For other gas disputes between Russia and Ukraine, including the current dispute, see Russia–Ukraine gas disputes. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: 2005–2006 Russia–Ukraine gas dispute – news · newspapers · books · scholar · JSTOR (January 2009) (Learn how and when to remove this message...

FIFA Women's World Rankings per 25 Agustus 2023.[1] Peringkat 20 besar per 25 Agustus 2023[1] Peringkat Perubahan Tim Poin 1 2  Swedia 2069.17 2 4  Spanyol 2051.84 3 2  Amerika Serikat 2051.21 4  Inggris 2030.14 5  Prancis 2004.17 6 4  Jerman 1987.67 7 2  Belanda 1984.5 8 3  Jepang 1961.35 9 1  Brasil 1949.41 10 3  Kanada 1944.84 11 1  Australia 1882.88 12 1  Denmark 1859.47 13 1  Norwegia 1856.45 14 1  Isl...

New Kingdom of LeónNuevo Reino de León (Spanish)1582–1821 Cross of Burgundy,flag of New Spain. Coat of arms Viceroyalty of New Spain in 1819.StatusSpanish colonyCapitalMonterreyCommon languagesSpanishReligion Roman CatholicismGovernmentMonarchyKing of Spain • January 16, 1556 - September 13, 1598 Philip II• 1813–1821 Ferdinand VII Royal Governor • 1580–1588 Luis de Carabajal y Cueva• 1795–1810 Simón de Herrera y Leyva Historical eraCo...

Not to be confused with Crown of Castile. Christian kingdom in Iberia (1065–1833) This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Kingdom of Castile – news · newspapers · books · scholar · JSTOR (May 2020) (Learn how and when to remove this message) Kingdom of CastileReino de Castilla (Spanish)Rēgnum...

Canadian basketball player Kia NurseNurse playing for the Canada women's national basketball team in 2018No. 10 – Los Angeles SparksPositionPoint guardLeagueWNBAPersonal informationBorn (1996-02-22) February 22, 1996 (age 28)Hamilton, Ontario, CanadaListed height6 ft 0 in (1.83 m)Listed weight181 lb (82 kg)Career informationHigh schoolSt. Thomas More(Hamilton, Ontario)CollegeUConn (2014–2018)WNBA draft2018: 1st round, 10th overall pickSelected by the ...

Theatre in which a resident company presents works from a specified repertoire Repertory redirects here. For the set of works one is ready to perform or are typically performed, see Repertoire. A repertory theatre, also called repertory, rep, true rep or stock, which are also called producing theatres, is a theatre in which a resident company presents works from a specified repertoire, usually in alternation or rotation.[1][2] Blue plaque marking the site of the Gaiety theatre...