Tropheryma whipplei

Como ler uma infocaixa de taxonomiaTropheryma whipplei
Taxocaixa sem imagem
Classificação científica
Reino: Bacteria
Filo: Actinobacteria
Classe: Actinobacteria
Ordem: Actinomycetales
Família: Cellulomonadaceae
Género: Tropheryma
Espécie: T. whipplei
Nome binomial
Tropheryma whipplei
La Scola et al. 2001

Tropheryma whipplei é uma espécie de bactéria na forma de bacilo gram-positivo[1] que causa a doença de Whipple, uma enfermidade caracterizada pela presença de artralgia, diarreia, dores abdominais, perda de peso, linfadenopatia febre e aumento da pigmentação da pele.

Epidemiologia

Afecta, maioritariamente, a homens jovens e de meia-idade.

Clínica

Esteatorreia associada a artralgias, febre, linfadenopatia e fadiga extrema. Pode haver envolvimento do SNC e do endocárdio. A demência é um sinal de mau prognóstico.

Histologia

Infiltração histiocítica da mucosa do inestino delgado (semelhante à infeção por Mycobacterium avium intracellulare em doentes com SIDA). Presença de macrófagos PAS+ na lâmina própria, que podem causar obstrução linfática.

Tratamento

Trimetropim-sulfametoxazol durante 1 ano.

Ligações externas

Referências

  1. ↑ La Scola B, Fenollar F, Fournier PE, Altwegg M, Mallet MN, Raoult D (2001), Description of Tropheryma whipplei gen. nov., sp. nov., the Whipple's disease bacillus, 51 (Pt 4), pp. 1471–9, PMID 11491348  Parâmetro desconhecido |publication= ignorado (ajuda)[ligação inativa]

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