Predefinição:PBB/796

Produtora de calcitonine

Estruturas disponíveis

Busca de ortólogos: PDBe, RCSB

Lista de códigos PDB
2JXZ

Identificadores

CALCA; CALC1; CGRP; CGRP-I; CGRP1; CT; KC

IDs externos

OMIM: 114130 MGI: 2151253 HomoloGene: 105263 ChEMBL: 5293 GeneCards: CALCA Gene

Ontologia do gene
Função molecular	•receptor binding •hormone activity •protein binding •calcitonin receptor binding •protein complex binding
Componente celular	•região extracelular •extracellular space •núcleo •citoplasma •neuronal cell body •terminal button
Processo biológico	•endothelial cell proliferation •vasculature development •neurological system process involved in regulation of systemic arterial blood pressure •vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure •regulation of heart rate •G-protein coupled receptor internalization •monocyte chemotaxis •protein phosphorylation •resposta inflamatória •leukocyte cell-cell adhesion •adenylate cyclase-activating G-protein coupled receptor signaling pathway •activation of adenylate cyclase activity •elevação da concentração iónica do cálcio citosólico •neuropeptide signaling pathway •sinalização célula-célula •embryo kkkkkkkkkkon •aging •feeding behavior •regulation of blood pressure •response to heat •negative regulation of calcium ion transport into cytosol •negative regulation of ossification •positive regulation of cAMP biosynthetic process •receptor internalization •negative regulation of neurological system process •activation of protein kinase activity •positive regulation of interleukin-1 alpha production •positive regulation of interleukin-8 production •vasodilation •endothelial cell migration •positive regulation of macrophage differentiation •negative regulation of osteoclast differentiation •positive regulation of adenylate cyclase activity •negative regulation of blood pressure •positive regulation of ossification •negative regulation of bone resorption •negative regulation of transcription, DNA-dependent •positive regulation of vasodilation •negative regulation of smooth muscle contraction •response to pain •regulation of inflammatory response •detection of temperature stimulus involved in sensory perception of pain •cytosolic calcium ion homeostasis •elevação da concentração iónica do cálcio citosólico involved in phospholipase C-activating G-protein coupled signaling pathway
Sources: Amigo / QuickGO

Padrões de expressão do ARN

Mais dados de expressão

Ortólogos

Espécies

Humano

Rato

ENSG00000110680

ENSMUSG00000030669

RefSeq (mRNA)

RefSeq (proteína)

Localização (UCSC)

Chr 11:
14.99 – 14.99 Mb

Chr 7:
114.63 – 114.64 Mb

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