Célula neurossecretora parvocelular

Célula neurossecretora parvocelular
Subclasse de secretory cell, célula endócrina, neurónio
Localização anatômica paraventricular nucleus of hypothalamus
Cell Ontology CL_1001505

As células neurossecretoras parvocelulares são neurônios pequenos do núcleo paraventricular (PVN) do hipotálamo. Os axônios das células neurossecretoras parvocelulares projetam-se para a eminência mediana, na base do cérebro, onde seus terminais nervosos neurossecretores liberam peptídeos nos vasos sanguíneos no sistema portal hipotálamo-hipófise. Os vasos sanguíneos transportam os peptídeos para a glândula pituitária anterior, onde regulam a secreção de hormônios na circulação sistêmica.[1][2]

Tipos

As células neurossecretoras parvocelulares incluem células que produzem:

Ver também

Referências

  1. Sawchenko. «Evidence for differential regulation of corticotropin-releasing factor and vasopressin immunoreactivities in parvocellular neurosecretory and autonomic-related projections of the paraventricular nucleus.». Brain Research. 437: 253–63. PMID 3325130. doi:10.1016/0006-8993(87)91641-6 
  2. Kovács. «Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons.». The Journal of Neuroscience. 16: 262–73. PMID 8613792. doi:10.1523/JNEUROSCI.16-01-00262.1996Acessível livremente 
  3. Ghamari-Langroudi. «Regulation of Thyrotropin-Releasing Hormone-Expressing Neurons in Paraventricular Nucleus of the Hypothalamus by Signals of Adiposity». Molecular Endocrinology. 24: 2366–2381. PMC 2999480Acessível livremente. PMID 20943814. doi:10.1210/me.2010-0203 
  4. Lennard. «Corticotropin-releasing hormone neurons in the paraventricular nucleus project to the external zone of the median eminence: a study combining retrograde labeling with immunocytochemistry.». Journal of Neuroendocrinology. 5: 175–81. PMID 8485552. doi:10.1111/j.1365-2826.1993.tb00378.x 
  5. Sawchenko. «Co-expression of corticotropin-releasing factor and vasopressin immunoreactivity in parvocellular neurosecretory neurons of the adrenalectomized rat.». Proceedings of the National Academy of Sciences of the United States of America. 81: 1883–7. PMC 345027Acessível livremente. PMID 6369332. doi:10.1073/pnas.81.6.1883 
  6. Watanobe. «In vivo release of neurotensin from the median eminence of ovariectomized estrogen-primed rats as estimated by push-pull perfusion: correlation with luteinizing hormone and prolactin surges.». Neuroendocrinology. 57: 760–4. PMID 8367038. doi:10.1159/000126434 

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