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(a) SCF contains three core subunits—the RING protein Rbx1, the cullin Cul1, and Skp1. Rbx1 binds the E2–ubiquitin conjugate. The target protein binds to an F-box protein that is bound to the enzyme core via interactions with the Skp1 subunit. After binding of a target protein to the F-box protein, the ubiquitin is transferred from E2 and attached via a peptide bond to a lysine side chain in the target protein. (b) A composite model structure for human SCF derived from X-ray structures of...

الدوري الفرنسي 1992–93 تفاصيل الموسم الدوري الفرنسي  النسخة 55  البلد فرنسا  التاريخ بداية:8 أغسطس 1992  نهاية:2 يونيو 1993  المنظم اتحاد فرنسا لكرة القدم  البطل أولمبيك مارسيليا  الهابطون نادي فالينسيان،  ونيم أولمبيك،  ونادي تولون  مباريات ملعوبة 380   �...

Sikorsky S-52 adalah sebuah helikopter serba-guna yang dikembangkan oleh Sikorsky Aircraft di akhir 1940-an. Helikopter ini digunakan oleh Angkatan Laut AS, Marinir, dan Coast Guard. Sikorsky S-52 adalah helikopter pertama AS dengan baling-baling sepenuhnya terbuat dari logam. Helikopter ini awalnya dilengkapi dua tempat duduk, tetapi kemudian dikembangkan menjadi empat di tipe S-52-2. Helikopter ini diberi nama HO5S-1 oleh Angkatan Laut AS dan Marine Corp, HO5S-1G oleh Coast Guard, dan YH-1...

United States historic placeOld Alexandria Public Library: Houses Louisiana History MuseumU.S. National Register of Historic Places Show map of LouisianaShow map of the United StatesLocation503 WashingtonAlexandria, LouisianaCoordinates31°18′31″N 92°26′43″W / 31.30861°N 92.44528°W / 31.30861; -92.44528Built1907ArchitectCrosby & Henkel; Caldwell Bros.Architectural styleBeaux ArtsNRHP reference No.88003225[1]Added to NRHPJanuary 19,...

Contract giving a seller the right to sell an asset to the buyer at a set price This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Put option – news · newspapers · books · scholar · JSTOR (November 2015) (Learn how and when to remove this template message) In finance, a put or put option is a derivative instrum...

16th Chief Minister of Madhya Pradesh, India Babulal Gaur16th Chief Minister of Madhya PradeshIn office23 August 2004 – 29 November 2005Preceded byUma BhartiSucceeded byShivraj Singh ChouhanMember of Madhya Pradesh Legislative AssemblyIn office1980 (1980)–2018 (2018)Preceded byLaxminarayan SharmaSucceeded byKrishna GaurConstituencyGovindpuraIn office1974 (1974)–1980 (1980)Preceded byConstituency establishedSucceeded bySatyanarayana AgarwalConstituencyBhopal ...

My Daughter, Geum Sa-wolPoster promosi untuk My Daughter, Geum Sa-wolGenreMelodrama KeluargaDitulis olehKim Soon-okPemeranBaek Jin-heeYoon Hyun-minJeon In-hwaPark Se-youngDo Sang-wooNegara asalKorea SelatanBahasa asliKoreaJmlh. episode50ProduksiLokasi produksiKorea Teman korea minSinematografiso helpfulDurasiSabtu dan Minggu pukul 22:00 (WSK)Rumah produksisudah berakhir sa wolRilis asliJaringanMunhwa Broadcasting CorporationRilis05 September 2015 (2015-09-05) –21 Februari 2016
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Cristiano Ronaldo is the competition's all-time top scorer with 140 goals The UEFA Champions League, known until 1992 as the European Champion Clubs' Cup or colloquially as the European Cup, is an annual association football cup competition organised by UEFA since 1955. Originally a straight knockout competition open only to champion clubs, the tournament was expanded during the 1990s to incorporate a round-robin group phase and more teams. The expansion resulted in more games being played, ...

Wormwood Street pictured in 2012. Wormwood Street is a short street in the City of London which runs between London Wall at its western end and a junction with Bishopsgate and Camomile Street in the east. It is a dual carriageway which forms part of the A1211 route between Barbican and Whitechapel. The nearest London Underground stations to Wormwood Street are Liverpool Street and Moorgate. It is within the London congestion charge zone. The postcode for the street is EC2. Etymology The name...

Classification term given to the first peoples who entered the American continents This article is about Paleolithic people of the Americas. For Paleolithic people of India, see South Asian Stone Age. For other aspects of the prehistory of the Americas, see Pre-Columbian era. Paleo-IndiansPaleo-Indians hunting a glyptodontHeinrich Harder (1858–1935), c. 1920. The Paleo-Indians, also known as the Lithic peoples, are the earliest known settlers of the Americas; the period's name, the Li...

Данио-рерио Научная классификация Домен:ЭукариотыЦарство:ЖивотныеПодцарство:ЭуметазоиБез ранга:Двусторонне-симметричныеБез ранга:ВторичноротыеТип:ХордовыеПодтип:ПозвоночныеИнфратип:ЧелюстноротыеГруппа:Костные рыбыКласс:Лучепёрые рыбыПодкласс:Новопёрые рыбыИн�...

1984 United States House of Representatives election in Alabama ← 1982 November 6, 1984 (1984-11-06) 1986 →   First party Second party   Leader Tom Bevill William Louis Dickinson Party Democratic Republican Leader since 1977 1981 Leader's seat 4th district 2nd district Seats won 5 2 Popular vote 821,773 308,182 Percentage 71.9% 27.0% --> Elections in Alabama Federal government Presidential elections 1820 1824 1828 1832 183...

Castle on the Isle of Wight, United Kingdom Carisbrooke CastleCarisbrooke, Isle of Wight, England The interior of Carisbrooke CastleCarisbrooke CastleCoordinates50°41′15″N 1°18′48″W / 50.6874°N 1.3133°W / 50.6874; -1.3133Grid referencegrid reference SZ486877TypeCastleSite informationOwnerManaged by English HeritageOpen tothe publicYesConditionCompleteSite historyBuiltBegun in 12th centuryIn useUntil 1944Garrison informationPastcommandersSir N...

Ahn TrioBackground informationOriginNew York CityGenresClassical, crossover, alternative rockYears active1989–presentLabelsSony Masterworks, EMI ClassicsMembers Maria Ahn Lucia Ahn Angella Ahn Websitewww.ahntrio.com The Ahn Trio is a classical piano trio composed of three sisters: Angella (violin), Lucia (piano), and Maria (cello) Ahn; Lucia and Maria are twins. Born in Seoul, Korea, they moved to New York City in 1981, and began their training at the Juilliard School. The sisters formed a ...

Antipope from 1378 to 1394 For the sixteenth-century pope, see Pope Clement VII.AntipopeClement VIICount of GenevaInterview between the duke of Anjou and pope Clement VII (seated) at Avignon, from Froissart's Chronicles.[1]Elected20 September 1378Papacy began20 September 1378?Papacy ended16 September 1394Predecessor Roman claimant: Urban VI Boniface IX Antipapal claimant: Nicholas V Successor Roman claimant: Boniface IX Antipapal (Avignonian) claimant: Benedict XIII Opposed toRoman cl...

Charles BonnetLahir(1720-03-13)13 Maret 1720Jenewa, Republik JenewaMeninggal20 Mei 1793(1793-05-20) (umur 73)Genthod dekat Jenewa, Republik JenewaWarga negaraWarga Republik JenewaKarier ilmiahBidangNaturalisTerinspirasiGottfried Wilhelm Leibniz Fellow of the Royal Society Charles Bonnet (bahasa Prancis: [bɔnɛ]; 13 Maret 1720 – 20 Mei 1793) adalah seorang naturalis dan penulis filsafat asal Jenewa.[1] Ia bertanggung jawab atas pencetusan istilah phyllotaxis...

Finnish politician Suna KymäläinenMember of the Finnish Parliamentfor South-Eastern Finland Personal detailsPolitical partySocial Democratic Party of Finland Suna Ellen Kymäläinen (born 15 September 1976) is a Finnish politician currently serving in the Parliament of Finland for the Social Democratic Party of Finland at the South-Eastern Finland constituency.[1] References ^ Eduskunta profile This article about a Social Democratic Party of Finland politician is a stub. You can hel...

Si Biang KerokGenre Drama Komedi PembuatScreenplay ProductionsSutradara Vemmy Sagita Robert Santosa Pemeran Ricky Harun Nina Zatulini Melody Prima Desta Indra Birowo Varissa Camelia Firda Kusller Yoga Pratama Lidya Kharisma Fanny Ghassani Mellissa Grace Penggubah lagu temaKerok BandLagu pembukaKalo Tibe Waktunye oleh Biang Kerok BandLagu penutupKalo Tibe Waktunye oleh Biang Kerok BandNegara asalIndonesiaBahasa asliBahasa IndonesiaJmlh. musim1Jmlh. episode148 (daftar episode)ProduksiProduser ...

Filipino businessman Manuel BonoanBonoan in 202340th Secretary of Public Works and HighwaysIncumbentAssumed office June 30, 2022PresidentBongbong MarcosPreceded byRoger Mercado (acting)ActingFebruary 1, 2007 – July 4, 2007PresidentGloria Macapagal ArroyoPreceded byHermogenes Ebdane Jr.Succeeded byHermogenes Ebdane Jr. Personal detailsNationalityFilipinoProfessionEngineer Manuel Manligas Bonoan[1] (born 1945/1946)[2] is a Filipino businessman and engineer who was...

Structuurformule van methylkwik. De X staat voor een willekeurig anion. Molecuulmodel van methylkwik. Methylkwik is een organometallisch kation met de formule [CH3Hg]+. Het is een bioaccumulatieve toxische verbinding. Structuur Methylkwik is de afkorting van monomethylkwik en moet eigenlijk het monomethylkwik-kation genoemd worden. Het bestaat uit een methylgroep (-CH3) die gebonden is aan een kwikatoom. Als een positief geladen ion wordt het makkelijk aangetrokken door anionen zoals het chlo...