Virus Alfuy

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Virus Alfuy
Immagine di Virus Alfuy mancante
Classificazione scientifica
DominioRiboviria
RegnoOrthornavirae
PhylumKitrinoviricota
ClasseFlasuviricetes
OrdineAmarillovirales
FamigliaFlaviviridae
GenereFlavivirus
SpecieMurray Valley encephalitis virus

Il virus Alfuy (ALFV, dall'inglese Alfuy virus) è un arbovirus della famiglia Flaviviridae, genere Flavivirus, appartiene al IV gruppo dei virus a ((+) ssRNA).[1]

Il virus è classificato come un sottotipo del flavivirus Murray Valley encefalite virus (MVEV); anche se al contrario di questo non provoca alcuna malattia nell'uomo.[2] Entrambi sono endemici in Australia e Papua Nuova Guinea.[3]

Si è però evidenziato come esso abbia una divergenza significativa sia di tipo antigenica, genetica e fenotipica con il MVEV. Di conseguenza, i dati suggeriscono che l'ALFV è una specie distinta all'interno del sierogruppo del virus dell'encefalite giapponese (JEV).[2]

Note

  1. ^ Claude M. Fauquet, M.A. Mayo, J. Maniloff, U. Desselberger and L.A. Ball, Virus Taxonomy: VIIIth Report of the International Committee on Taxonomy of Viruses, Academic Press, 15 luglio 2005, pp. 1257–, ISBN 978-0-08-057548-3.
  2. ^ a b May FJ, Lobigs M, Lee E, Gendle DJ, Mackenzie JS, Broom AK, Conlan JV, Hall RA, Biological, antigenic and phylogenetic characterization of the flavivirus Alfuy, in J. Gen. Virol., vol. 87, Pt 2, 2006, pp. 329–37, DOI:10.1099/vir.0.81252-0, PMID 16432019.
  3. ^ Prow NA, May FJ, Westlake DJ, Hurrelbrink RJ, Biron RM, Leung JY, McMinn PC, Clark DC, Mackenzie JS, Lobigs M, Khromykh AA, Hall RA, Determinants of attenuation in the envelope protein of the flavivirus Alfuy, in J. Gen. Virol., vol. 92, Pt 10, 2011, pp. 2286–96, DOI:10.1099/vir.0.034793-0, PMID 21733886.

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