Mixedema

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Mixedema
Specialitàendocrinologia
Eziologiaipotiroidismo
Classificazione e risorse esterne (EN)
ICD-9-CM244.9
OMIM255900
MeSHD009230
MedlinePlus000353
eMedicine1103765

Il termine mixedema descrive una condizione patologica caratterizzata da edema del sottocute dovuta ad accumulo di mucopolisaccaridi, tipico dell'ipotiroidismo[1] e di alcune forme di ipertiroidismo (come il morbo di Graves-Basedow).

Epidemiologia

Alcune delle complicanze, come la follia da mixedema, sono abbastanza comuni negli anziani.

Sintomatologia

Fra i sintomi e i segni clinici ritroviamo edema, raucedine, gonfiore locale al viso (in particolare le labbra), inoltre la normale funzione motoria viene alterata e ne consegue un rallentamento dei movimenti. Altre manifestazioni poi dipendono dalla particolare situazione della complicanza.

Tipologia

Esistono alcune complicanze riferite al mixedema:

Patologie associate

La si riscontra nella malattia di Graves[3] e nella tiroidite di Hashimoto.

Prognosi

Infausta nel caso di coma, con una mortalità che arriva al 50% dei casi.

Note

  1. ^ autore W. D. James, T. G. Berger, et al., Andrews' Diseases of the Skin: clinical Dermatology, Saunders Elsevier, 2006, pp. a p. 535, ISBN 0-7216-2921-0.
  2. ^ Research Laboratories Merck, The Merck Manual quinta edizione pag 1269, Milano, Springer-Verlag, 2008, ISBN 978-88-470-0707-9.
  3. ^ ni-Ranjbar S, Mohajeri-Tehrani MR., Localized myxedema of the toe: a rare presentation of graves' dermopathy., in Arch Iran Med., vol. 11, maggio 2008, pp. 326-329.

Bibliografia

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Controllo di autoritàThesaurus BNCF 62095 · LCCN (ENsh85089446 · BNF (FRcb11979622f (data) · J9U (ENHE987007558135905171
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